[Yb(AAZTA)(H2O)]−: an unconventional ParaCEST MRI probe.

Daniela Delli Castelli; Lorenzo Tei; Fabio Carniato; Silvio Aime; Mauro Botta

doi:10.1039/c8cc00193f

[Yb(AAZTA)(H2O)]−: an unconventional ParaCEST MRI probe.

Daniela Delli Castelli
, Lorenzo Tei
, Fabio Carniato
, Silvio Aime
, Mauro Botta

Dipartimento di Scienze e Innovazione Tecnologica

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

An unexpectedly slow exchange rate has been observed for the coordinated water molecule of [Yb(AAZTA)(H₂O)]^- using ¹H-NMR and CEST-MRI studies. This made it possible for the first time to exploit the bound water molecule of a Ln^III complex with carboxylic donor groups for CEST imaging. This result envisages the development of a new family of thermodynamically stable ParaCEST probes based on anionic chelates.

Lingua originale	Inglese
pagine (da-a)	2004-2007
Numero di pagine	4
Rivista	Chemical Communications
Volume	54
Numero di pubblicazione	16
DOI	https://doi.org/10.1039/c8cc00193f
Stato di pubblicazione	Pubblicato - 1 lug 2018

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10.1039/c8cc00193f

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abstract = "An unexpectedly slow exchange rate has been observed for the coordinated water molecule of [Yb(AAZTA)(H2O)]- using 1H-NMR and CEST-MRI studies. This made it possible for the first time to exploit the bound water molecule of a LnIII complex with carboxylic donor groups for CEST imaging. This result envisages the development of a new family of thermodynamically stable ParaCEST probes based on anionic chelates.",

author = "\{Delli Castelli\}, Daniela and Lorenzo Tei and Fabio Carniato and Silvio Aime and Mauro Botta",

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AU - Carniato, Fabio

AU - Aime, Silvio

AU - Botta, Mauro

PY - 2018/7/1

Y1 - 2018/7/1

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AB - An unexpectedly slow exchange rate has been observed for the coordinated water molecule of [Yb(AAZTA)(H2O)]- using 1H-NMR and CEST-MRI studies. This made it possible for the first time to exploit the bound water molecule of a LnIII complex with carboxylic donor groups for CEST imaging. This result envisages the development of a new family of thermodynamically stable ParaCEST probes based on anionic chelates.

UR - https://www.scopus.com/pages/publications/85042434768

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JO - Chemical Communications

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ER -

[Yb(AAZTA)(H2O)]−: an unconventional ParaCEST MRI probe.

Abstract

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