VRG: A database of vascular dysfunctions related genes

Sara Zanivan; Davide Corà; Michele Caselle; Federico Bussolino

doi:10.1016/j.camwa.2006.12.097

VRG: A database of vascular dysfunctions related genes

Sara Zanivan, Davide Corà, Michele Caselle, Federico Bussolino

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

Heart and vascular defects occur in a large number of hereditary and sporadic human diseases as a result of a complex interplay of genetic factors. Since genome sequencing of many organisms disclosed similarities among genomes, animal models are crucial for the discovery of genes involved in those pathological processes. Therefore we propose a VRG database, in which human data have been manually managed and integrated with mouse information in order to create a catalogue of genes involved in vascular diseases.

Lingua originale	Inglese
pagine (da-a)	1068-1073
Numero di pagine	6
Rivista	Computers and Mathematics with Applications
Volume	55
Numero di pubblicazione	5
DOI	https://doi.org/10.1016/j.camwa.2006.12.097
Stato di pubblicazione	Pubblicato - mar 2008
Pubblicato esternamente	Sì

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10.1016/j.camwa.2006.12.097

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title = "VRG: A database of vascular dysfunctions related genes",

abstract = "Heart and vascular defects occur in a large number of hereditary and sporadic human diseases as a result of a complex interplay of genetic factors. Since genome sequencing of many organisms disclosed similarities among genomes, animal models are crucial for the discovery of genes involved in those pathological processes. Therefore we propose a VRG database, in which human data have been manually managed and integrated with mouse information in order to create a catalogue of genes involved in vascular diseases.",

keywords = "Animal models, Database, Genome, Human vascular diseases",

author = "Sara Zanivan and Davide Cor{\`a} and Michele Caselle and Federico Bussolino",

note = "Funding Information: We thank Guido Serini and Marco Arese for critical reading of the manuscript. This study was supported by Associazione Italiana per la Ricerca sul Cancro, Istituto Superiore di Sanit{\'a}. (AIDS National Projects), Ministero dell Universit{\'a} e della Ricerca (MIUR) (60% and PRIN 2004 projects), Ministero della Salute (Ricerca Finalizzata 2002–2004), Regione Piemonte, European Community (LSHM-CT-2003-503251) ( http://www.engv.org ), FIRB (Fondo per gli Investimenti della Ricerca di Base) from the Italian Ministry of the University and Scientific Research, number RBNE03B8KK006.",

year = "2008",

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doi = "10.1016/j.camwa.2006.12.097",

language = "English",

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T2 - A database of vascular dysfunctions related genes

AU - Zanivan, Sara

AU - Corà, Davide

AU - Caselle, Michele

AU - Bussolino, Federico

N1 - Funding Information: We thank Guido Serini and Marco Arese for critical reading of the manuscript. This study was supported by Associazione Italiana per la Ricerca sul Cancro, Istituto Superiore di Sanitá. (AIDS National Projects), Ministero dell Universitá e della Ricerca (MIUR) (60% and PRIN 2004 projects), Ministero della Salute (Ricerca Finalizzata 2002–2004), Regione Piemonte, European Community (LSHM-CT-2003-503251) ( http://www.engv.org ), FIRB (Fondo per gli Investimenti della Ricerca di Base) from the Italian Ministry of the University and Scientific Research, number RBNE03B8KK006.

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AB - Heart and vascular defects occur in a large number of hereditary and sporadic human diseases as a result of a complex interplay of genetic factors. Since genome sequencing of many organisms disclosed similarities among genomes, animal models are crucial for the discovery of genes involved in those pathological processes. Therefore we propose a VRG database, in which human data have been manually managed and integrated with mouse information in order to create a catalogue of genes involved in vascular diseases.

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DO - 10.1016/j.camwa.2006.12.097

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JO - Computers and Mathematics with Applications

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VRG: A database of vascular dysfunctions related genes

Abstract

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