TY - JOUR
T1 - Treatment options in skeletal localizations of hairy cell leukemia
T2 - A systematic review on the role of radiation therapy
AU - Filippi, Andrea R.
AU - Franco, Pierfrancesco
AU - Marinone, Carlo
AU - Tarella, Corrado
AU - Ricardi, Umberto
PY - 2007/11
Y1 - 2007/11
N2 - Skeletal localizations are a rare complication in hairy cell leukaemia patients, with an extimated incidence of 3%. These lesions, mainly osteolytic, can occur at various sites and are almost always symptomatic. Localized radiation therapy (RT) has been extensively used as effective palliative treatment in such cases, with different total doses and fractionation schedules. In this article, a systematic review of all reported cases with osseous complications is presented, to underline the role of RT and to define the most appropriate approach in this subset of patients.
AB - Skeletal localizations are a rare complication in hairy cell leukaemia patients, with an extimated incidence of 3%. These lesions, mainly osteolytic, can occur at various sites and are almost always symptomatic. Localized radiation therapy (RT) has been extensively used as effective palliative treatment in such cases, with different total doses and fractionation schedules. In this article, a systematic review of all reported cases with osseous complications is presented, to underline the role of RT and to define the most appropriate approach in this subset of patients.
UR - http://www.scopus.com/inward/record.url?scp=35548994227&partnerID=8YFLogxK
U2 - 10.1002/ajh.20785
DO - 10.1002/ajh.20785
M3 - Review article
SN - 0361-8609
VL - 82
SP - 1017
EP - 1021
JO - American Journal of Hematology
JF - American Journal of Hematology
IS - 11
ER -