TRASUTA: The Effect of the Structural Rigidity of a Mesocyclic AAZTA-like Chelating Agent on the Thermodynamic, Kinetic, and Structural Properties of Some Divalent Metal and Ga3+ Complexes

Ileana Merdzo, Fabio Travagin, Mariangela Boccalon, Enzo Alessio, Luciano Lattuada, Zsolt Baranyai, Giovanni Battista GIOVENZANA

Risultato della ricerca: Contributo su rivistaArticolo in rivistapeer review

Abstract

Mesocyclic chelating agents such as AAZTA and its derivatives have been recently reported to overcome the relatively low thermodynamic stability of metal complexes of acyclic chelating agents and the slow complexation kinetics of macrocyclic chelating agents. This work reports the preparation of a spirobicyclic hexadentate AAZTA-like chelating agent (TRASUTA) and the investigation of the thermodynamic, kinetic, and structural properties of the corresponding chelates with the PET-relevant Ga3+ and selected metal ions. A combination of analytical techniques allowed identification of a coordination isomerization process, involving the coordinating side arms and the inversion of a nitrogen atom and leading to lower thermodynamic and kinetic inertness with respect to mononuclear mesocyclic analogues. The bicyclic system of TRASUTA retains significant dynamics despite the conformational constraint imposed by the spiro-fusion, resulting in a lower stability of the corresponding metal chelates.
Lingua originaleInglese
pagine (da-a)12525-12537
Numero di pagine13
RivistaInorganic Chemistry
Volume63
Numero di pubblicazione27
DOI
Stato di pubblicazionePubblicato - 2024

Keywords

  • chelating agents mesocyclic AAZTA transition metals NMR

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