The second hit of DNA methylation

Annalisa Di Ruscio; Robert S. Welner; Daniel G. Tenen; Giovanni Amabile

doi:10.1080/23723556.2015.1093690

The second hit of DNA methylation

Annalisa Di Ruscio
, Robert S. Welner
, Daniel G. Tenen
, Giovanni Amabile

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

Gene expression programs are tightly regulated by heritable “epigenetic” information, which is stored as chemical modifications of histones and DNA. With the recent development of sequencing-based epigenome mapping technologies and cancer cellular reprogramming, the tools are now in hand to analyze the epigenetic contribution to human cancer.

Lingua originale	Inglese
Numero di articolo	e1093690
Rivista	Molecular and Cellular Oncology
Volume	3
Numero di pubblicazione	3
DOI	https://doi.org/10.1080/23723556.2015.1093690
Stato di pubblicazione	Pubblicato - 3 mag 2016
Pubblicato esternamente	Sì

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10.1080/23723556.2015.1093690

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title = "The second hit of DNA methylation",

abstract = "Gene expression programs are tightly regulated by heritable “epigenetic” information, which is stored as chemical modifications of histones and DNA. With the recent development of sequencing-based epigenome mapping technologies and cancer cellular reprogramming, the tools are now in hand to analyze the epigenetic contribution to human cancer.",

author = "\{Di Ruscio\}, Annalisa and Welner, \{Robert S.\} and Tenen, \{Daniel G.\} and Giovanni Amabile",

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year = "2016",

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AB - Gene expression programs are tightly regulated by heritable “epigenetic” information, which is stored as chemical modifications of histones and DNA. With the recent development of sequencing-based epigenome mapping technologies and cancer cellular reprogramming, the tools are now in hand to analyze the epigenetic contribution to human cancer.

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The second hit of DNA methylation

Abstract

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