TY - JOUR
T1 - The role of radiation therapy in vulvar cancer
T2 - Review of the current literature
AU - Sciacero, Piera
AU - Cante, Domenico
AU - Piva, Cristina
AU - Borca, Valeria Casanova
AU - Petrucci, Edoardo
AU - Gastaldi, Luca
AU - La Porta, Maria Rosa
AU - Franco, Pierfrancesco
N1 - Publisher Copyright:
© 2016 Wichtig Publishing
PY - 2017/9/1
Y1 - 2017/9/1
N2 - The purpose of this article is to discuss the current role of radiation therapy in vulvar cancer and especially to review the recent literature relative to the use of intensity-modulated radiotherapy (IMRT) in disease management. Owing to the low incidence of vulvar cancer, at present there are no available results of cooperative prospective trials. As evidenced in dosimetric and preliminary retrospective clinical studies, the use of IMRT has resulted in superior normal tissue sparing and lower rates of acute and chronic toxicities compared to previous studies that used conventional approaches. Data on long-term outcomes in these patients remain limited.
AB - The purpose of this article is to discuss the current role of radiation therapy in vulvar cancer and especially to review the recent literature relative to the use of intensity-modulated radiotherapy (IMRT) in disease management. Owing to the low incidence of vulvar cancer, at present there are no available results of cooperative prospective trials. As evidenced in dosimetric and preliminary retrospective clinical studies, the use of IMRT has resulted in superior normal tissue sparing and lower rates of acute and chronic toxicities compared to previous studies that used conventional approaches. Data on long-term outcomes in these patients remain limited.
KW - Conventional 2D-3D radiotherapy
KW - Intensity-modulated radiation therapy
KW - Vulvar squamous cancer
UR - http://www.scopus.com/inward/record.url?scp=85031091898&partnerID=8YFLogxK
U2 - 10.5301/tj.5000529
DO - 10.5301/tj.5000529
M3 - Review article
SN - 0300-8916
VL - 103
SP - 422
EP - 429
JO - Tumori
JF - Tumori
IS - 5
ER -
