The Potential for Plant Derivatives against Acrylamide Neurotoxicity

O. O. Adewale, J. M. Brimson, O. A. Odunola, M. A. Gbadegesin, S. E. Owumi, Ciro Isidoro, T. Tencomnao

Risultato della ricerca: Contributo su rivistaArticolo di reviewpeer review

Abstract

Certain industrial chemicals and food contaminants have been demonstrated to possess neurotoxic activity and have been suspected to cause brain-related disorders in humans. Acrylamide (ACR), a confirmed neurotoxicant, can be found in trace amount in commonly consumed human aliments as a result of food processing or cooking. This discovery aroused a great concern in the public, and increasing efforts are continuously geared towards the resolution of this serious threat. The broad chemical diversity of plants may offer the resources for novel antidotes against neurotoxicants. With the goal of attenuating neurotoxicity of ACR, several plants extracts or derivatives have been employed. This review presents the plants and their derivatives that have been shown most active against ACR-induced neurotoxicity, with a focus on their origin, pharmacological activity, and antidote effects.

Lingua originaleInglese
pagine (da-a)978-985
Numero di pagine8
RivistaPhytotherapy Research
Volume29
Numero di pubblicazione7
DOI
Stato di pubblicazionePubblicato - 1 lug 2015

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