The Metabolic Fate of isoCombretastatin A-4 in Human Liver Microsomes: Identification, Synthesis and Biological Evaluation of Metabolites

Mohamed Ali Soussi; Silvio Aprile; Samir Messaoudi; Olivier Provot; Erika DelGrosso; Jérôme Bignon; Joëlle Dubois; Jean Daniel Brion; Giorgio Grosa; Mouad Alami

doi:10.1002/cmdc.201100193

The Metabolic Fate of isoCombretastatin A-4 in Human Liver Microsomes: Identification, Synthesis and Biological Evaluation of Metabolites

Mohamed Ali Soussi
, Silvio Aprile
, Samir Messaoudi
, Olivier Provot
, Erika DelGrosso
, Jérôme Bignon
, Joëlle Dubois
, Jean Daniel Brion
, Giorgio Grosa
, Mouad Alami

Dipartimento di Scienze del Farmaco

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Lingua originale	Inglese
pagine (da-a)	1781-1788
Numero di pagine	8
Rivista	ChemMedChem
Volume	6
Numero di pubblicazione	10
DOI	https://doi.org/10.1002/cmdc.201100193
Stato di pubblicazione	Pubblicato - 4 ott 2011

Accesso al documento

10.1002/cmdc.201100193

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@article{b565a641cf1d48d29992a061989f20d0,

title = "The Metabolic Fate of isoCombretastatin A-4 in Human Liver Microsomes: Identification, Synthesis and Biological Evaluation of Metabolites",

keywords = "Anticancer agents, Cytotoxicity, Drug metabolism, Isocombretastatin A-4, Tubulin",

author = "Soussi, \{Mohamed Ali\} and Silvio Aprile and Samir Messaoudi and Olivier Provot and Erika DelGrosso and J{\'e}r{\^o}me Bignon and Jo{\"e}lle Dubois and Brion, \{Jean Daniel\} and Giorgio Grosa and Mouad Alami",

year = "2011",

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doi = "10.1002/cmdc.201100193",

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T1 - The Metabolic Fate of isoCombretastatin A-4 in Human Liver Microsomes

T2 - Identification, Synthesis and Biological Evaluation of Metabolites

AU - Soussi, Mohamed Ali

AU - Aprile, Silvio

AU - Messaoudi, Samir

AU - Provot, Olivier

AU - DelGrosso, Erika

AU - Bignon, Jérôme

AU - Dubois, Joëlle

AU - Brion, Jean Daniel

AU - Grosa, Giorgio

AU - Alami, Mouad

PY - 2011/10/4

Y1 - 2011/10/4

KW - Anticancer agents

KW - Cytotoxicity

KW - Drug metabolism

KW - Isocombretastatin A-4

KW - Tubulin

UR - https://www.scopus.com/pages/publications/80053391280

U2 - 10.1002/cmdc.201100193

DO - 10.1002/cmdc.201100193

M3 - Article

SN - 1860-7179

VL - 6

SP - 1781

EP - 1788

JO - ChemMedChem

JF - ChemMedChem

IS - 10

ER -