The mammalian sulfated glycolipid sulfatide: Synthesis and biological implications

Federica Compostella; Luigi Panza; Fiamma Ronchetti

doi:10.1016/j.crci.2011.09.011

The mammalian sulfated glycolipid sulfatide: Synthesis and biological implications

Federica Compostella, Luigi Panza, Fiamma Ronchetti

Dipartimento di Scienze del Farmaco

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

Sulfatide is one of the most relevant endogenous acidic glycolipids found in mammal membranes, ubiquitously present in various tissues. The review will briefly introduce the physiopathological role of sulfatide, then focusing mainly on synthetic aspects related to the preparation of this molecule and of analogues thereof, as tools to better understand its biological role, its involvement in pathogenesis and to stimulate the research towards development of new derivatives for biomedical applications.

Lingua originale	Inglese
pagine (da-a)	37-45
Numero di pagine	9
Rivista	Comptes Rendus Chimie
Volume	15
Numero di pubblicazione	1
DOI	https://doi.org/10.1016/j.crci.2011.09.011
Stato di pubblicazione	Pubblicato - gen 2012

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10.1016/j.crci.2011.09.011

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abstract = "Sulfatide is one of the most relevant endogenous acidic glycolipids found in mammal membranes, ubiquitously present in various tissues. The review will briefly introduce the physiopathological role of sulfatide, then focusing mainly on synthetic aspects related to the preparation of this molecule and of analogues thereof, as tools to better understand its biological role, its involvement in pathogenesis and to stimulate the research towards development of new derivatives for biomedical applications.",

keywords = "Carbohydrates, Galactosylceramide, Glycosphingolipids, Glycosylation",

author = "Federica Compostella and Luigi Panza and Fiamma Ronchetti",

note = "Funding Information: The authors gratefully thank the University of Milan and the University of Piemonte Orientale for financial support.",

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doi = "10.1016/j.crci.2011.09.011",

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KW - Galactosylceramide

KW - Glycosphingolipids

KW - Glycosylation

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The mammalian sulfated glycolipid sulfatide: Synthesis and biological implications

Abstract

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