The insulin signal and its effects on the pyruvate dehydrogenase complex in cirulating lymphocytes of obese children

M. Curto, M. Piccinini, F. Cerutti, I. Rabbone, M. Mostert, C. Sacchetti, R. Bruno, M. T. Rinaudo

Risultato della ricerca: Contributo su rivistaArticolo in rivistapeer review

Abstract

1. 1. Studies have shown that in circulating lymphocytes pyruvate dehydrogenase (PDH) is responsive to insulin. 2. 2. To improve existing knowledge on how insulin influences PDH behaviour, situations in which cell responsiveness to insulin is impaired could be of interest. 3. 3. PDH behaviour in circulating lymphocytes from obese children, with high plasma insulin levels and normal glucose tolerance, was examined. 4. 4. Masking and unmasking processes of insulin receptors on the plasma membrane appear to modulate the enzyme response to insulin.

Lingua originaleInglese
pagine (da-a)831-837
Numero di pagine7
RivistaInternational Journal of Biochemistry
Volume24
Numero di pubblicazione5
DOI
Stato di pubblicazionePubblicato - mag 1992
Pubblicato esternamente

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