The effect of chronic atropine administration on mouse motility and on ACh levels in the central nervous system

Luigi Molinengo, Anna Fundarò, Marco Orsetti

Risultato della ricerca: Contributo su rivistaArticolo in rivistapeer review

Abstract

Changes in mouse motility and CNS cortical and subcortical ACh levels were studied after chronic (20 days) administration of 30, 40 and 60 mg/kg/day atropine. An increase in motility similar to that induced by tropine administration was observed, whereas the ACh levels reduction caused by acute administration was not repeated. These results suggest that changes in mouse motility caused by atropine are not correlated to its modification of ACh levels in the CNS.

Lingua originaleInglese
pagine (da-a)1075-1077
Numero di pagine3
RivistaPharmacology Biochemistry and Behavior
Volume32
Numero di pubblicazione4
DOI
Stato di pubblicazionePubblicato - apr 1989
Pubblicato esternamente

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