The adulthood of MRD detection in MCL

In this issue of Blood, Pott and colleagues correlate clinical outcome and MRD results in MCL.¹ The analysis by real-time quantitative PCR of 259 patients included in 2 international randomized trials indicated MRD as an independent outcome predictor. The good large-scale applicability and high predictive value indicate that MRD detection is ready to be assessed as a decision-making tool in MCL.