Tear film osmolarity, ocular surface disease and glaucoma: A review

Paolo Fogagnolo, Giulia Torregrossa, Laura Tranchina, Antonio Ferreras, Stefano De Cillà, Antoine Labbé, Michele Figus, Laura Ottobelli, Luca Rossetti

Risultato della ricerca: Contributo su rivistaArticolo di reviewpeer review

Abstract

Glaucoma is the second leading cause of blindness in the world, affecting more than 60 million people globally. In order to reduce the progression of the disease, both medical and surgical treatments are used. Frequent side effects of both treatments include a range of modifications of the ocular surface grouped as the Ocular Surface Disease (OSD), which include Dry Eye Disease (DED). DED and other OSD negatively impact on the success of anti-glaucoma treatments and reduce the adherence to medical therapies. Tear film osmolarity (TFO) is a relatively novel test which has become a hallmark of DED. The aim of this paper was to review the association between OSD, DED and glaucoma in view of published TFO data, and to discuss future fields of research and treatments on the topic of glaucoma iatrogenic damage.

Lingua originaleInglese
pagine (da-a)4241-4252
Numero di pagine12
RivistaCurrent Medicinal Chemistry
Volume26
Numero di pubblicazione22
DOI
Stato di pubblicazionePubblicato - 2019
Pubblicato esternamente

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