Synthesis of novel carborane-hybrids based on a triazine scaffold for boron neutron capture therapy

Silvia Ronchi; Davide Prosperi; Federica Compostella; Luigi Panza

doi:10.1055/s-2004-822897

Synthesis of novel carborane-hybrids based on a triazine scaffold for boron neutron capture therapy

Silvia Ronchi, Davide Prosperi, Federica Compostella, Luigi Panza

Dipartimento di Scienze del Farmaco

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

Cyanuric chloride has been used as a scaffold for the synthesis of potential agents for BNCT containing a carborane cluster, a sugar moiety as hydrophilic arm and an amino acid for the conjugation with bioactive molecules; this approach is, in principle, particularly suitable for a combinatorial approach.

Lingua originale	Inglese
pagine (da-a)	1007-1010
Numero di pagine	4
Rivista	Synlett
Numero di pubblicazione	6
DOI	https://doi.org/10.1055/s-2004-822897
Stato di pubblicazione	Pubblicato - 6 mag 2004

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10.1055/s-2004-822897

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title = "Synthesis of novel carborane-hybrids based on a triazine scaffold for boron neutron capture therapy",

abstract = "Cyanuric chloride has been used as a scaffold for the synthesis of potential agents for BNCT containing a carborane cluster, a sugar moiety as hydrophilic arm and an amino acid for the conjugation with bioactive molecules; this approach is, in principle, particularly suitable for a combinatorial approach.",

keywords = "Amino acids, Boron, Carborane cluster, Glycosides, Medicinal chemistry",

author = "Silvia Ronchi and Davide Prosperi and Federica Compostella and Luigi Panza",

year = "2004",

month = may,

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doi = "10.1055/s-2004-822897",

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AU - Ronchi, Silvia

AU - Prosperi, Davide

AU - Compostella, Federica

AU - Panza, Luigi

PY - 2004/5/6

Y1 - 2004/5/6

N2 - Cyanuric chloride has been used as a scaffold for the synthesis of potential agents for BNCT containing a carborane cluster, a sugar moiety as hydrophilic arm and an amino acid for the conjugation with bioactive molecules; this approach is, in principle, particularly suitable for a combinatorial approach.

AB - Cyanuric chloride has been used as a scaffold for the synthesis of potential agents for BNCT containing a carborane cluster, a sugar moiety as hydrophilic arm and an amino acid for the conjugation with bioactive molecules; this approach is, in principle, particularly suitable for a combinatorial approach.

KW - Amino acids

KW - Boron

KW - Carborane cluster

KW - Glycosides

KW - Medicinal chemistry

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U2 - 10.1055/s-2004-822897

DO - 10.1055/s-2004-822897

M3 - Article

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JO - Synlett

JF - Synlett

IS - 6

ER -

Synthesis of novel carborane-hybrids based on a triazine scaffold for boron neutron capture therapy

Abstract

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