Synthesis of building blocks of human milk oligosaccharides. Fucosylated derivatives of the lacto- and neolacto-series

Barbara La Ferla, Davide Prosperi, Luigi Lay, Giovanni Russo, Luigi Panza

Risultato della ricerca: Contributo su rivistaArticolo in rivistapeer review

Abstract

The synthesis of protected fucosylated derivatives of a Galβ(1→3)GlcNAc and of lactosamine Galβ(1→4)GlcNAc building blocks contained in human milk oligosaccharides is described. Both chemical and enzymatic methods have been exploited for selective protection of the disaccharide. Fucosylation of the appropriate derivatives allowed an easy and relatively short access to different products from common precursors.

Lingua originaleInglese
pagine (da-a)1333-1342
Numero di pagine10
RivistaCarbohydrate Research
Volume337
Numero di pubblicazione15
DOI
Stato di pubblicazionePubblicato - 3 set 2002

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