Symptomatic cerebrospinal fluid HIV-1 escape in two patients on second-line antiretroviral therapy in Uganda

Kenneth Ssebambulidde; Ivan Segawa; Eva Laker; Mohammed Lamorde; Barbara Castelnouvo; Noeline Nakasujja; Andrea CALCAGNO

doi:10.1093/omcr/omy132

Symptomatic cerebrospinal fluid HIV-1 escape in two patients on second-line antiretroviral therapy in Uganda

Kenneth Ssebambulidde
, Ivan Segawa
, Eva Laker
, Mohammed Lamorde
, Barbara Castelnouvo
, Noeline Nakasujja
, Andrea CALCAGNO

Dipartimento di Medicina Traslazionale

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

Two HIV-infected individuals on second-line atazanavir-based antiretroviral therapy presented with neuropsychiatric symptoms. Cerebrospinal fluid HIV RNA was higher than plasma HIV RNA and antiretroviral regimens' optimization led to prompt resolution of symptoms in one. Patients on second-line atazanavir-based antiretroviral therapy with documented previous treatment failure may be at risk of symptomatic cerebrospinal fluid escape.

Lingua originale	Inglese
pagine (da-a)	79-82
Numero di pagine	4
Rivista	Oxford Medical Case Reports
Volume	2019
Numero di pubblicazione	2
DOI	https://doi.org/10.1093/omcr/omy132
Stato di pubblicazione	Pubblicato - 2019

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10.1093/omcr/omy132

https://hdl.handle.net/11579/216808

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abstract = "Two HIV-infected individuals on second-line atazanavir-based antiretroviral therapy presented with neuropsychiatric symptoms. Cerebrospinal fluid HIV RNA was higher than plasma HIV RNA and antiretroviral regimens' optimization led to prompt resolution of symptoms in one. Patients on second-line atazanavir-based antiretroviral therapy with documented previous treatment failure may be at risk of symptomatic cerebrospinal fluid escape.",

author = "Kenneth Ssebambulidde and Ivan Segawa and Eva Laker and Mohammed Lamorde and Barbara Castelnouvo and Noeline Nakasujja and Andrea CALCAGNO",

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AU - Ssebambulidde, Kenneth

AU - Segawa, Ivan

AU - Laker, Eva

AU - Lamorde, Mohammed

AU - Castelnouvo, Barbara

AU - Nakasujja, Noeline

AU - CALCAGNO, Andrea

PY - 2019

Y1 - 2019

N2 - Two HIV-infected individuals on second-line atazanavir-based antiretroviral therapy presented with neuropsychiatric symptoms. Cerebrospinal fluid HIV RNA was higher than plasma HIV RNA and antiretroviral regimens' optimization led to prompt resolution of symptoms in one. Patients on second-line atazanavir-based antiretroviral therapy with documented previous treatment failure may be at risk of symptomatic cerebrospinal fluid escape.

AB - Two HIV-infected individuals on second-line atazanavir-based antiretroviral therapy presented with neuropsychiatric symptoms. Cerebrospinal fluid HIV RNA was higher than plasma HIV RNA and antiretroviral regimens' optimization led to prompt resolution of symptoms in one. Patients on second-line atazanavir-based antiretroviral therapy with documented previous treatment failure may be at risk of symptomatic cerebrospinal fluid escape.

UR - https://iris.uniupo.it/handle/11579/216808

U2 - 10.1093/omcr/omy132

DO - 10.1093/omcr/omy132

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JO - Oxford Medical Case Reports

JF - Oxford Medical Case Reports

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Symptomatic cerebrospinal fluid HIV-1 escape in two patients on second-line antiretroviral therapy in Uganda

Abstract

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