Surface properties and cell response of low metal ion release Ti-6Al-7Nb alloy after multi-step chemical and thermal treatments

Silvia Spriano, Michela Bosetti, Marco Bronzoni, Enrica Vernè, Giovanni Maina, Valerio Bergo, Mario Cannas

Risultato della ricerca: Contributo su rivistaArticolo in rivistapeer review

Abstract

Ti-6Al-7Nb samples treated by innovative multi-step chemical and thermal processes were characterized in order to evaluate their surface properties and cell interaction. The main object was to asses if the treatments were effective in order to obtain a surface presenting at the same time bone-like apatite induction ability, low metal ion release, good cell response and high protein binding. The morphology, crystallographic structure, porosity and wettability of the treated materials were investigated, as well as their interaction with simulated body fluid during soaking for different times. Cytotoxicity, protein adsorption tests and in vitro fibroblast and osteoblast-like cell cultures were also performed.

Lingua originaleInglese
pagine (da-a)1219-1229
Numero di pagine11
RivistaBiomaterials
Volume26
Numero di pubblicazione11
DOI
Stato di pubblicazionePubblicato - apr 2005

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