Study on the interaction between gelatin and polyurethanes derived from fatty acids

R. J. González-Paz; G. Lligadas; J. C. Ronda; M. Galià; A. M. Ferreira; F. Boccafoschi; G. Ciardelli; V. Cádiz

doi:10.1002/jbm.a.34407

Study on the interaction between gelatin and polyurethanes derived from fatty acids

R. J. González-Paz, G. Lligadas, J. C. Ronda, M. Galià, A. M. Ferreira, F. Boccafoschi, G. Ciardelli, V. Cádiz

Dipartimento di Scienze della Salute

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

In this study, gelatin was blended to proprietary noncytotoxic polyurethanes (PU) derived from vegetable oils with different weight ratios, as material for the preparation of novel biomedical products. The PU/gelatin blends were characterized for their morphology through scanning electron microscopy. Mechanical and thermal properties, chemical interactions between components, degradation behavior, surface properties, cell adhesion, and bioactivity were investigated as a function of the protein content. Higher blend miscibility was observed for the amorphous PUs, derived from oleic acid. Properties of PU/gelatin films were strongly influenced by the concentration of gelatin in the films. Gelatin enhanced the hydrophilicity, bioactivity, and cell adhesion of PUs.

Lingua originale	Inglese
pagine (da-a)	1036-1046
Numero di pagine	11
Rivista	Journal of Biomedical Materials Research - Part A
Volume	101 A
Numero di pubblicazione	4
DOI	https://doi.org/10.1002/jbm.a.34407
Stato di pubblicazione	Pubblicato - apr 2013

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10.1002/jbm.a.34407

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title = "Study on the interaction between gelatin and polyurethanes derived from fatty acids",

abstract = "In this study, gelatin was blended to proprietary noncytotoxic polyurethanes (PU) derived from vegetable oils with different weight ratios, as material for the preparation of novel biomedical products. The PU/gelatin blends were characterized for their morphology through scanning electron microscopy. Mechanical and thermal properties, chemical interactions between components, degradation behavior, surface properties, cell adhesion, and bioactivity were investigated as a function of the protein content. Higher blend miscibility was observed for the amorphous PUs, derived from oleic acid. Properties of PU/gelatin films were strongly influenced by the concentration of gelatin in the films. Gelatin enhanced the hydrophilicity, bioactivity, and cell adhesion of PUs.",

keywords = "Bioactivity, Blend, Fatty acid, Gelatin, Immunocytochemistry, Polyurethane",

author = "Gonz{\'a}lez-Paz, {R. J.} and G. Lligadas and Ronda, {J. C.} and M. Gali{\`a} and Ferreira, {A. M.} and F. Boccafoschi and G. Ciardelli and V. C{\'a}diz",

year = "2013",

month = apr,

doi = "10.1002/jbm.a.34407",

language = "English",

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AU - González-Paz, R. J.

AU - Lligadas, G.

AU - Ronda, J. C.

AU - Galià, M.

AU - Ferreira, A. M.

AU - Boccafoschi, F.

AU - Ciardelli, G.

AU - Cádiz, V.

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AB - In this study, gelatin was blended to proprietary noncytotoxic polyurethanes (PU) derived from vegetable oils with different weight ratios, as material for the preparation of novel biomedical products. The PU/gelatin blends were characterized for their morphology through scanning electron microscopy. Mechanical and thermal properties, chemical interactions between components, degradation behavior, surface properties, cell adhesion, and bioactivity were investigated as a function of the protein content. Higher blend miscibility was observed for the amorphous PUs, derived from oleic acid. Properties of PU/gelatin films were strongly influenced by the concentration of gelatin in the films. Gelatin enhanced the hydrophilicity, bioactivity, and cell adhesion of PUs.

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KW - Blend

KW - Fatty acid

KW - Gelatin

KW - Immunocytochemistry

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M3 - Article

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Study on the interaction between gelatin and polyurethanes derived from fatty acids

Abstract

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