Strategy of human cytomegalovirus to escape interferon beta-induced APOBEC3G editing activity

Keyphrases

• Human Cytomegalovirus 100%
• Interferon-β (IFN-β) 100%
• APOBEC3G 100%
• Editing Activity 100%
• Catalytic Subunit 46%
• Apolipoprotein B (Apo B) 46%
• Enzyme Catalysis 46%
• Subunit 3 46%
• Cytomegalovirus Infection 33%
• Cytomegalovirus Replication 26%
• Overexpression 13%
• Human Foreskin Fibroblasts 13%
• APOBEC3A 13%
• Restriction Factor 6%
• Upstream Open Reading Frame (uORF) 6%
• Fibroblasts 6%
• Gene Expression 6%
• Viral Genome 6%
• Selective Pressure 6%
• Viral 6%
• Gene Products 6%
• Immune Defense 6%
• Innate Immune Response 6%
• DNA Virus 6%
• Retrovirus 6%
• RNA Virus 6%
• Defense Mechanisms 6%
• Single-stranded DNA (ssDNA) 6%
• Deamination 6%
• Bioinformatics Methods 6%
• Escape Strategy 6%
• DNA Cytosine Deaminase 6%
• Mutational Robustness 6%
• Multiple Viral Infections 6%
• Decidual Tissue 6%
• Gene Family Member 6%
• Induced mutagenesis 6%
• Maternal-fetal Interface 6%
• DNA Editing 6%
• Innate Immune Effectors 6%
• Nucleotide Motifs 6%
• Intrinsic Immunity 6%
• Antiviral Potential 6%

Immunology and Microbiology

• Human Cytomegalovirus 100%
• Beta Interferon 100%
• APOBEC3G 100%
• Enzyme Active Site 35%
• Apolipoprotein B 35%
• Cytomegalovirus Infection 25%
• Fibroblast 15%
• Innate Immune System 5%
• Viral Disease 5%
• Open Reading Frame 5%
• Upregulation 5%
• Multigene Family 5%
• Gene Expression 5%
• Mutagenesis 5%
• Gene Product 5%
• Immune Evasion 5%
• RNA Virus 5%
• Virus Genome 5%
• Retrovirus 5%
• DNA Strand 5%
• Nucleotide Motif 5%
• Deamination 5%
• Intrinsic Immunity 5%
• DNA Virus 5%
• Bioinformatics 5%

Biochemistry, Genetics and Molecular Biology

• Human Cytomegalovirus 100%
• APOBEC3G 100%
• Interferon 100%
• Enzyme Active Site 35%
• Apolipoprotein B 35%
• Fibroblast 15%
• Open Reading Frame 5%
• Upregulation 5%
• Gene Expression 5%
• Mutagenesis 5%
• Gene Product 5%
• Innate Immunity 5%
• Multigene Family 5%
• Retrovirus 5%
• DNA Strand 5%
• Virus Genome 5%
• Immune Evasion 5%
• Cytosine Deaminase 5%
• Deamination 5%
• Nucleotide Motif 5%
• RNA Virus 5%
• DNA Virus 5%
• Bioinformatics 5%