Steric control of lanthanide hydration state: Fast water exchange at gadolinium in a mono-amide 'DOTA' complex

Aileen Congreve; David Parker; Eliana Gianolio; Mauro Botta

doi:10.1039/B402230K

Steric control of lanthanide hydration state: Fast water exchange at gadolinium in a mono-amide 'DOTA' complex

Aileen Congreve, David Parker, Eliana Gianolio, Mauro Botta

Dipartimento di Scienze e Innovazione Tecnologica

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

Detailed analyses of the solution structure and exchange dynamics of two sets of homologous mono-amide triacetate lanthanide complexes (Ln = Eu, Gd) of cyclen have been undertaken. The complex [LnL¹], bearing an N-linked CH₂CH₂NHCO-pyridyl moiety, forms mono-aqua (q = 1) species in solution and the Gd complex undergoes rapid water exchange (k_ex = 11 × 10⁷s^-1, 298 K) as a result of the steric destabilisation of the Ln-water binding interaction. The homologous complex with a C-3 spacing chain, [LnL²], forms a q = 0 species.

Lingua originale	Inglese
pagine (da-a)	1441-1445
Numero di pagine	5
Rivista	Dalton Transactions
Numero di pubblicazione	9
DOI	https://doi.org/10.1039/B402230K
Stato di pubblicazione	Pubblicato - 7 mag 2004

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title = "Steric control of lanthanide hydration state: Fast water exchange at gadolinium in a mono-amide 'DOTA' complex",

abstract = "Detailed analyses of the solution structure and exchange dynamics of two sets of homologous mono-amide triacetate lanthanide complexes (Ln = Eu, Gd) of cyclen have been undertaken. The complex [LnL1], bearing an N-linked CH2CH2NHCO-pyridyl moiety, forms mono-aqua (q = 1) species in solution and the Gd complex undergoes rapid water exchange (kex = 11 × 107s-1, 298 K) as a result of the steric destabilisation of the Ln-water binding interaction. The homologous complex with a C-3 spacing chain, [LnL2], forms a q = 0 species.",

author = "Aileen Congreve and David Parker and Eliana Gianolio and Mauro Botta",

year = "2004",

month = may,

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doi = "10.1039/B402230K",

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T1 - Steric control of lanthanide hydration state

T2 - Fast water exchange at gadolinium in a mono-amide 'DOTA' complex

AU - Congreve, Aileen

AU - Parker, David

AU - Gianolio, Eliana

AU - Botta, Mauro

PY - 2004/5/7

Y1 - 2004/5/7

N2 - Detailed analyses of the solution structure and exchange dynamics of two sets of homologous mono-amide triacetate lanthanide complexes (Ln = Eu, Gd) of cyclen have been undertaken. The complex [LnL1], bearing an N-linked CH2CH2NHCO-pyridyl moiety, forms mono-aqua (q = 1) species in solution and the Gd complex undergoes rapid water exchange (kex = 11 × 107s-1, 298 K) as a result of the steric destabilisation of the Ln-water binding interaction. The homologous complex with a C-3 spacing chain, [LnL2], forms a q = 0 species.

AB - Detailed analyses of the solution structure and exchange dynamics of two sets of homologous mono-amide triacetate lanthanide complexes (Ln = Eu, Gd) of cyclen have been undertaken. The complex [LnL1], bearing an N-linked CH2CH2NHCO-pyridyl moiety, forms mono-aqua (q = 1) species in solution and the Gd complex undergoes rapid water exchange (kex = 11 × 107s-1, 298 K) as a result of the steric destabilisation of the Ln-water binding interaction. The homologous complex with a C-3 spacing chain, [LnL2], forms a q = 0 species.

UR - https://www.scopus.com/pages/publications/2642525373

U2 - 10.1039/B402230K

DO - 10.1039/B402230K

M3 - Article

SN - 1477-9226

SP - 1441

EP - 1445

JO - Dalton Transactions

JF - Dalton Transactions

IS - 9

ER -

Steric control of lanthanide hydration state: Fast water exchange at gadolinium in a mono-amide 'DOTA' complex

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