Specialization determines outcomes in inflammation and cancer

Antonio SICA

doi:10.1038/s41590-023-01592-0

Specialization determines outcomes in inflammation and cancer

Antonio SICA

Dipartimento di Scienze del Farmaco

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

The functional heterogeneity of macrophages has ontological and microenvironmental bases, and differentially affects pathology. In pancreatitis, tissue-resident macrophages promote protective fibrosis that favors the maintenance of pancreatic homeostasis. In pancreatic ductal adenocarcinoma, they promote tumor progression by facilitating stromal desmoplasia.

Lingua originale	Inglese
pagine (da-a)	1399-1401
Numero di pagine	3
Rivista	Nature Immunology
Volume	9
DOI	https://doi.org/10.1038/s41590-023-01592-0
Stato di pubblicazione	Pubblicato - 2023

OSS delle Nazioni Unite

Questo processo contribuisce al raggiungimento dei seguenti obiettivi di sviluppo sostenibile

SDG 3 Salute e benessere

Keywords

cancer
inflammaiton
macrophages
pancreatic cancer

Accesso al documento

10.1038/s41590-023-01592-0

https://hdl.handle.net/11579/179274

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title = "Specialization determines outcomes in inflammation and cancer",

abstract = "The functional heterogeneity of macrophages has ontological and microenvironmental bases, and differentially affects pathology. In pancreatitis, tissue-resident macrophages promote protective fibrosis that favors the maintenance of pancreatic homeostasis. In pancreatic ductal adenocarcinoma, they promote tumor progression by facilitating stromal desmoplasia.",

keywords = "cancer, inflammaiton, macrophages, pancreatic cancer, cancer, inflammaiton, macrophages, pancreatic cancer",

author = "Antonio SICA",

year = "2023",

doi = "10.1038/s41590-023-01592-0",

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KW - cancer

KW - inflammaiton

KW - macrophages

KW - pancreatic cancer

KW - cancer

KW - inflammaiton

KW - macrophages

KW - pancreatic cancer

UR - https://iris.uniupo.it/handle/11579/179274

U2 - 10.1038/s41590-023-01592-0

DO - 10.1038/s41590-023-01592-0

M3 - Article

SN - 1529-2908

VL - 9

SP - 1399

EP - 1401

JO - Nature Immunology

JF - Nature Immunology

ER -

Specialization determines outcomes in inflammation and cancer

Abstract

OSS delle Nazioni Unite

Keywords

Accesso al documento

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