Specialization determines outcomes in inflammation and cancer

Antonio SICA; Massimo Lazzeri

doi:10.1038/s41590-023-01592-0

Specialization determines outcomes in inflammation and cancer

Antonio SICA, Massimo Lazzeri

Dipartimento di Scienze del Farmaco

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

The functional heterogeneity of macrophages has ontological and microenvironmental bases, and differentially affects pathology. In pancreatitis, tissue-resident macrophages promote protective fibrosis that favors the maintenance of pancreatic homeostasis. In pancreatic ductal adenocarcinoma, they promote tumor progression by facilitating stromal desmoplasia.

Lingua originale	Inglese
pagine (da-a)	1399-1401
Numero di pagine	3
Rivista	Nature Immunology
Volume	24
Numero di pubblicazione	9
DOI	https://doi.org/10.1038/s41590-023-01592-0
Stato di pubblicazione	Pubblicato - 2023

Keywords

Pancreatic cancer
macrophages

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Questo processo contribuisce al raggiungimento dei seguenti obiettivi di sviluppo sostenibile

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10.1038/s41590-023-01592-0

https://hdl.handle.net/11579/203942

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title = "Specialization determines outcomes in inflammation and cancer",

abstract = "The functional heterogeneity of macrophages has ontological and microenvironmental bases, and differentially affects pathology. In pancreatitis, tissue-resident macrophages promote protective fibrosis that favors the maintenance of pancreatic homeostasis. In pancreatic ductal adenocarcinoma, they promote tumor progression by facilitating stromal desmoplasia.",

keywords = "Pancreatic cancer, macrophages, Pancreatic cancer, macrophages",

author = "Antonio SICA and Massimo Lazzeri",

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AU - Lazzeri, Massimo

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KW - macrophages

KW - Pancreatic cancer

KW - macrophages

UR - https://iris.uniupo.it/handle/11579/203942

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DO - 10.1038/s41590-023-01592-0

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JO - Nature Immunology

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ER -

Specialization determines outcomes in inflammation and cancer

Abstract

Keywords

OSS delle Nazioni Unite

Accesso al documento

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