Space-Efficient Merging of Succinct de Bruijn Graphs

Lavinia Egidi, Felipe A. Louza, Giovanni Manzini

Risultato della ricerca: Capitolo in libro/report/atti di convegnoContributo a conferenzapeer review

Abstract

We propose a new algorithm for merging succinct representations of de Bruijn graphs introduced in [Bowe et al. WABI 2012]. Our algorithm is based on the lightweight BWT merging approach by Holt and McMillan [Bionformatics 2014, ACM-BCB 2014]. Our algorithm has the same asymptotic cost of the state of the art tool for the same problem presented by Muggli et al. [bioRxiv 2017, Bioinformatics 2019], but it uses less than half of its working space. A novel important feature of our algorithm, not found in any of the existing tools, is that it can compute the Variable Order succinct representation of the union graph within the same asymptotic time/space bounds.

Lingua originaleInglese
Titolo della pubblicazione ospiteString Processing and Information Retrieval - 26th International Symposium, SPIRE 2019, Proceedings
EditorNieves R. Brisaboa, Simon J. Puglisi
EditoreSPRINGER
Pagine337-351
Numero di pagine15
ISBN (stampa)9783030326852
DOI
Stato di pubblicazionePubblicato - 2019
Evento26th International Symposium on String Processing and Information Retrieval, SPIRE 2019 - Segovia, Spain
Durata: 7 ott 20199 ott 2019

Serie di pubblicazioni

NomeLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume11811 LNCS
ISSN (stampa)0302-9743
ISSN (elettronico)1611-3349

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???event.eventtypes.event.conference???26th International Symposium on String Processing and Information Retrieval, SPIRE 2019
Paese/TerritorioSpain
CittàSegovia
Periodo7/10/199/10/19

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