Simultaneous determination of acidic and basic-neutral pesticides in water at ppt concentration level by ion-interaction micro-HPLC/MS

A. Cappiello, G. Famiglini, F. Mangani, S. Angelino, M. C. Gennaro

Risultato della ricerca: Contributo su rivistaArticolo in rivistapeer review

Abstract

A new ion-interaction micro-HPLC method, for the simultaneous separation of acidic and base-neutral pesticides, was coupled to a capillary-scale particle beam LC/MS interface for El mass spectrometric detection of the analytes. The method was employed for analysis of tap water in which a large number of functionally different pesticides can be determined in a single run. Capillary-scale technology of the LC/MS apparatus yields full compatibility with hexylammonium phosphate, a nonvolatile salt used as ion- interaction reagent in the HPLC mobile phase, and provides an excellent sensitivity with instrument detection limits (IDLs) ranging between 0.07 and 0.7 ng in SIM mode. Method sensitivity lower than 0.1 ppb in water was achieved using a large-volume injection technique specifically developed for capillary columns typical flow rates.

Lingua originaleInglese
pagine (da-a)3905-3910
Numero di pagine6
RivistaEnvironmental Science & Technology
Volume33
Numero di pubblicazione21
DOI
Stato di pubblicazionePubblicato - 1 nov 1999
Pubblicato esternamente

Fingerprint

Entra nei temi di ricerca di 'Simultaneous determination of acidic and basic-neutral pesticides in water at ppt concentration level by ion-interaction micro-HPLC/MS'. Insieme formano una fingerprint unica.

Cita questo