Sequential multicomponent synthesis of α-ketoimides, from acyl chlorides, isocyanides, and silver salts of carboxylic acids

Fabio La Spisa; Gian Cesare Tron

doi:10.1016/j.tetlet.2014.10.135

Sequential multicomponent synthesis of α-ketoimides, from acyl chlorides, isocyanides, and silver salts of carboxylic acids

Fabio La Spisa, Gian Cesare Tron

Dipartimento di Scienze del Farmaco

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

A sequential multicomponent synthesis among acyl chlorides, isocyanides, and silver salts of carboxylic acids was developed to synthesize α-ketoimides. The latter undergo an intramolecular aza-Wittig reaction to afford 2-acylquinazolinones.

Lingua originale	Inglese
pagine (da-a)	7060-7063
Numero di pagine	4
Rivista	Tetrahedron Letters
Volume	55
Numero di pubblicazione	51
DOI	https://doi.org/10.1016/j.tetlet.2014.10.135
Stato di pubblicazione	Pubblicato - 17 dic 2014

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10.1016/j.tetlet.2014.10.135

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title = "Sequential multicomponent synthesis of α-ketoimides, from acyl chlorides, isocyanides, and silver salts of carboxylic acids",

abstract = "A sequential multicomponent synthesis among acyl chlorides, isocyanides, and silver salts of carboxylic acids was developed to synthesize α-ketoimides. The latter undergo an intramolecular aza-Wittig reaction to afford 2-acylquinazolinones.",

keywords = "Acyl chlorides, Isocyanides, Multicomponent reaction, Nef reaction",

author = "\{La Spisa\}, Fabio and Tron, \{Gian Cesare\}",

year = "2014",

month = dec,

day = "17",

doi = "10.1016/j.tetlet.2014.10.135",

language = "English",

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journal = "Tetrahedron Letters",

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T1 - Sequential multicomponent synthesis of α-ketoimides, from acyl chlorides, isocyanides, and silver salts of carboxylic acids

AU - La Spisa, Fabio

AU - Tron, Gian Cesare

PY - 2014/12/17

Y1 - 2014/12/17

N2 - A sequential multicomponent synthesis among acyl chlorides, isocyanides, and silver salts of carboxylic acids was developed to synthesize α-ketoimides. The latter undergo an intramolecular aza-Wittig reaction to afford 2-acylquinazolinones.

AB - A sequential multicomponent synthesis among acyl chlorides, isocyanides, and silver salts of carboxylic acids was developed to synthesize α-ketoimides. The latter undergo an intramolecular aza-Wittig reaction to afford 2-acylquinazolinones.

KW - Acyl chlorides

KW - Isocyanides

KW - Multicomponent reaction

KW - Nef reaction

U2 - 10.1016/j.tetlet.2014.10.135

DO - 10.1016/j.tetlet.2014.10.135

M3 - Article

SN - 0040-4039

VL - 55

SP - 7060

EP - 7063

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 51

ER -

Sequential multicomponent synthesis of α-ketoimides, from acyl chlorides, isocyanides, and silver salts of carboxylic acids

Abstract

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