Role of functional imaging in treatment plan optimization of stereotactic body radiation therapy for liver cancer

Berardino De Bari; Raphael Jumeau; Letizia Deantonio; Salim Adib; Sarah Godin; Michele Zeverino; Raphael Moeckli; Jean Bourhis; John O. Prior; Mahmut Ozsahin

doi:10.5301/tj.5000523

Role of functional imaging in treatment plan optimization of stereotactic body radiation therapy for liver cancer

Berardino De Bari
, Raphael Jumeau
, Letizia Deantonio
, Salim Adib
, Sarah Godin
, Michele Zeverino
, Raphael Moeckli
, Jean Bourhis
, John O. Prior
, Mahmut Ozsahin

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

We report the first known instance of the clinical use of 99mTc-mebrofenin hepatobiliary scintigraphy (HBS) for the optimization of radiotherapy treatment planning and for the follow-up of acute toxicity in a patient undergoing stereotactic body radiation therapy for hepatocellular carcinoma. In our experience, HBS allowed the identification and the sparing of more functioning liver areas, thus potentially reducing the risk of radiation-induced liver toxicity.

Lingua originale	Inglese
pagine (da-a)	e21-e24
Rivista	Tumori
Volume	102
Numero di pubblicazione	5
DOI	https://doi.org/10.5301/tj.5000523
Stato di pubblicazione	Pubblicato - 1 set 2016
Pubblicato esternamente	Sì

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title = "Role of functional imaging in treatment plan optimization of stereotactic body radiation therapy for liver cancer",

abstract = "We report the first known instance of the clinical use of 99mTc-mebrofenin hepatobiliary scintigraphy (HBS) for the optimization of radiotherapy treatment planning and for the follow-up of acute toxicity in a patient undergoing stereotactic body radiation therapy for hepatocellular carcinoma. In our experience, HBS allowed the identification and the sparing of more functioning liver areas, thus potentially reducing the risk of radiation-induced liver toxicity.",

keywords = "Hepatocellular carcinoma, Liver cancer, Stereotactic body radiation therapy (SBRT), Tc-mebrofenin hepatobiliary scintigraphy (HBS), Toxicity",

author = "\{De Bari\}, Berardino and Raphael Jumeau and Letizia Deantonio and Salim Adib and Sarah Godin and Michele Zeverino and Raphael Moeckli and Jean Bourhis and Prior, \{John O.\} and Mahmut Ozsahin",

year = "2016",

month = sep,

day = "1",

doi = "10.5301/tj.5000523",

language = "English",

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T1 - Role of functional imaging in treatment plan optimization of stereotactic body radiation therapy for liver cancer

AU - De Bari, Berardino

AU - Jumeau, Raphael

AU - Deantonio, Letizia

AU - Adib, Salim

AU - Godin, Sarah

AU - Zeverino, Michele

AU - Moeckli, Raphael

AU - Bourhis, Jean

AU - Prior, John O.

AU - Ozsahin, Mahmut

PY - 2016/9/1

Y1 - 2016/9/1

N2 - We report the first known instance of the clinical use of 99mTc-mebrofenin hepatobiliary scintigraphy (HBS) for the optimization of radiotherapy treatment planning and for the follow-up of acute toxicity in a patient undergoing stereotactic body radiation therapy for hepatocellular carcinoma. In our experience, HBS allowed the identification and the sparing of more functioning liver areas, thus potentially reducing the risk of radiation-induced liver toxicity.

AB - We report the first known instance of the clinical use of 99mTc-mebrofenin hepatobiliary scintigraphy (HBS) for the optimization of radiotherapy treatment planning and for the follow-up of acute toxicity in a patient undergoing stereotactic body radiation therapy for hepatocellular carcinoma. In our experience, HBS allowed the identification and the sparing of more functioning liver areas, thus potentially reducing the risk of radiation-induced liver toxicity.

KW - Hepatocellular carcinoma

KW - Liver cancer

KW - Stereotactic body radiation therapy (SBRT)

KW - Tc-mebrofenin hepatobiliary scintigraphy (HBS)

KW - Toxicity

UR - https://www.scopus.com/pages/publications/84995592114

U2 - 10.5301/tj.5000523

DO - 10.5301/tj.5000523

M3 - Article

SN - 0300-8916

VL - 102

SP - e21-e24

JO - Tumori

JF - Tumori

IS - 5

ER -

Role of functional imaging in treatment plan optimization of stereotactic body radiation therapy for liver cancer

Abstract

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