TY - JOUR
T1 - Revealing the Potency of Growth Factors in Bovine Colostrum
AU - Yalçıntaş, Yalçın Mert
AU - Duman, Hatice
AU - López, Jose M.Miranda
AU - Portocarrero, Alicia C.Mondragón
AU - Lombardo, Mauro
AU - Khallouki, Farid
AU - Koch, Wojciech
AU - Bordiga, Matteo
AU - El-Seedi, Hesham
AU - Raposo, António
AU - Alves, Jose Luiz de Brito
AU - Karav, Sercan
N1 - Publisher Copyright:
© 2024 by the authors.
PY - 2024/7
Y1 - 2024/7
N2 - Colostrum is a nutritious milk synthesized by mammals during the postpartum period, and its rich bioactive components has led to a global increase in the consumption of bovine colostrum as a supplement. Bovine colostrum contains key components such as immunoglobulins, oligosaccharides, lactoferrin and lysozyme. It is a special supplement source due to its natural, high bioavailability and high concentrations of growth factors. Growth factors are critical to many physiological functions, and considering its presence in the colostrum, further research must be conducted on its safe application in many bodily disorders. Growth factors contribute to wound healing, muscle and bone development, and supporting growth in children. Additionally, the molecular mechanisms have been explored, highlighting the growth factors roles in cell proliferation, tissue regeneration, and the regulation of immune responses. These findings are crucial for understanding the potential health effects of bovine colostrum, ensuring its safe use, and forming a basis for future clinical applications. This review article examines the growth factors concentration in bovine colostrum, their benefits, clinical studies, and molecular mechanisms.
AB - Colostrum is a nutritious milk synthesized by mammals during the postpartum period, and its rich bioactive components has led to a global increase in the consumption of bovine colostrum as a supplement. Bovine colostrum contains key components such as immunoglobulins, oligosaccharides, lactoferrin and lysozyme. It is a special supplement source due to its natural, high bioavailability and high concentrations of growth factors. Growth factors are critical to many physiological functions, and considering its presence in the colostrum, further research must be conducted on its safe application in many bodily disorders. Growth factors contribute to wound healing, muscle and bone development, and supporting growth in children. Additionally, the molecular mechanisms have been explored, highlighting the growth factors roles in cell proliferation, tissue regeneration, and the regulation of immune responses. These findings are crucial for understanding the potential health effects of bovine colostrum, ensuring its safe use, and forming a basis for future clinical applications. This review article examines the growth factors concentration in bovine colostrum, their benefits, clinical studies, and molecular mechanisms.
KW - colostrum
KW - growth factors
KW - health benefits
KW - immune responses
KW - nutritional supplements
UR - http://www.scopus.com/inward/record.url?scp=85199633355&partnerID=8YFLogxK
U2 - 10.3390/nu16142359
DO - 10.3390/nu16142359
M3 - Review article
SN - 2072-6643
VL - 16
JO - Nutrients
JF - Nutrients
IS - 14
M1 - 2359
ER -