Repurposing of psychotropic drugs for cancer therapy

Keyphrases

• Cancer Therapy 100%
• Repurposing 100%
• Spiperone 100%
• Pimozide 60%
• Fluoxetine 60%
• Apoptosis 40%
• Cell Death 40%
• Cytotoxicity 40%
• Fluspirilene 40%
• Penfluridol 40%
• Nefazodone 40%
• Cancer Cell Lines 20%
• In Cancer 20%
• Ca2+ 20%
• Cancer Types 20%
• Homeostasis 20%
• Intracellular Calcium 20%
• Endoplasmic Reticulum 20%
• Overall Survival 20%
• Colorectal Cancer Cells 20%
• Stem Cells 20%
• 3-methyladenine (3-MA) 20%
• Ca2+ Release 20%
• Epidemiological Study 20%
• MCF-7 Cells 20%
• Cytotoxic Activity 20%
• New Therapeutic Approaches 20%
• Autophagy Inhibitor 20%
• Cancer Incidence 20%
• Ca2+ Overload 20%
• Breast 20%
• Lysosomal Compartment 20%
• Clinical Development 20%
• Membrane Depolarization 20%
• Lysosomal Cathepsins 20%
• Caspase 20%
• Cytotoxic Compounds 20%
• Cell Cycle Block 20%
• Drug Repositioning 20%
• Endoplasmic Reticulum Stress Protein 20%
• G1 Phase 20%
• Unfolded Protein Response 20%
• Response Activation 20%
• Phospholipidosis 20%
• Drug Treatment 20%
• Ebastine 20%
• Mitochondrial Depolarization 20%
• Reduced Cells 20%
• Amphiphilic Structure 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Malignant Neoplasm 100%
• Psychotropic Agent 100%
• Repurposing 100%
• Spiperone 83%
• Calcium Ion 50%
• Pimozide 50%
• Fluoxetine 50%
• Cytotoxicity 50%
• Nefazodone 33%
• Penfluridol 33%
• Fluspirilene 33%
• Colorectal Carcinoma 16%
• Pharmacotherapy 16%
• Overall Survival 16%
• 3 Methyladenine 16%
• Caspase 16%
• Phospholipidosis 16%
• Cathepsin 16%
• Cancer Incidence 16%
• Drug Repositioning 16%
• Ebastine 16%

Biochemistry, Genetics and Molecular Biology

• Spiperone 100%
• Cytotoxicity 60%
• Pimozide 60%
• Fluoxetine 60%
• Cell Death 40%
• Cancer Cell 40%
• Programmed Cell Death 40%
• Nefazodone 40%
• Homeostasis 20%
• Calcium Cell Level 20%
• Upregulation 20%
• Overall Survival 20%
• Autophagy 20%
• Membrane Depolarization 20%
• Caspase 20%
• Endoplasmic Reticulum Stress 20%
• Cell Cycle 20%
• G1 Phase 20%
• Cathepsin 20%
• Mitochondrial Membrane 20%
• Outer Mitochondrial Membrane 20%
• Unfolded Protein Response 20%
• Cancer Incidence 20%
• Drug Therapy 20%
• Ebastine 20%