Relative potencies of testosterone and 5α-dihydrotestosterone on crowing and cloacal gland growth in the Japanese quail (Coturnix coturnix japonica)

J. Balthazart, M. Schumacher, G. Malacarne

Risultato della ricerca: Contributo su rivistaArticolo in rivistapeer review

Abstract

It has been suggested that testosterone is less effective at inducing crowing behaviour in young birds than in adults because of the presence of higher levels of steroid 5β-reductase in the young brain, which converts testosterone to inactive 5β-reduced metabolites. This hypothesis was tested indirectly by comparing the relative potencies of 5α-dihydrotestosterone (5α-DHT), which cannot be converted to 5β-metabolites, and testosterone at inducing crowing in young gonadectomized male and female quail. The promotion of cloacal gland growth by these treatments was also assessed since there are no age-related changes in 5β-reductase in this organ. Silicone elastomer implants (2.5, 5 and 10 mm) containing 5α-DHT were more effective at stimulating crowing than similar implants of testosterone whilst there was little difference in their potency at inducing cloacal gland growth. These results are consistent with the hypothesis that brain steroid 5β-reductase regulates the behavioural activity of testosterone in the brain of young birds.

Lingua originaleInglese
pagine (da-a)19-23
Numero di pagine5
RivistaJournal of Endocrinology
Volume100
Numero di pubblicazione1
DOI
Stato di pubblicazionePubblicato - 1984
Pubblicato esternamente

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