Pt(IV) Bifunctional Prodrug Containing 2-(2-Propynyl)octanoato Axial Ligand: Induction of Immunogenic Cell Death on Colon Cancer ^a

Keyphrases

• Bifunctional 100%
• Colon Cancer 100%
• Immunogenic Cell Death 100%
• Pt(IV) Prodrug 100%
• Axial Ligand 100%
• Prodrug 100%
• Propynol 100%
• Cyclohexane 75%
• Diamine 75%
• Tumor Mass 50%
• Oxaliplatin 50%
• Platinum(IV) 50%
• Tumor 25%
• Histone Deacetylase Inhibitor (HDACi) 25%
• Nephrotoxicity 25%
• Order of Magnitude 25%
• Colon Cancer Cells 25%
• Balb C Mice 25%
• Pt(IV) Complexes 25%
• Hepatotoxicity 25%
• In Vitro Activity 25%
• HT-29 25%
• Lipophilicity 25%
• In Vivo Experiment 25%
• HCT116 25%
• Enantiomerically Enriched 25%
• Syngeneic 25%
• CD8+ Cytotoxic T Lymphocytes 25%
• C26 Colon Carcinoma 25%
• SW480 25%
• Synthesis, Characterization 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Neoplasm 100%
• Colon Carcinoma 100%
• Cyclohexane 100%
• Immunogenic Cell Death 100%
• Prodrug 100%
• Oxaliplatin 66%
• Platinum 66%
• Histone Deacetylase Inhibitor 33%
• Nephrotoxicity 33%
• Bagg Albino Mouse 33%
• CD8 Antigen 33%
• Hepatotoxicity 33%
• Lipophilicity 33%