TY - JOUR
T1 - Providing a nurse-led complex nursing INtervention FOcused on quality of life assessment on advanced cancer patients
T2 - The INFO-QoL pilot trial
AU - the INFO-QoL Collaborative Group
AU - Catania, Gianluca
AU - Zanini, Milko
AU - Signori, Alessio
AU - Dal Molin, A.
AU - Pilastri, Paola
AU - Bottino, Marta
AU - Cervetti, Claudia
AU - Aleo, Giuseppe
AU - Sasso, Loredana
AU - Bagnasco, Annamaria
AU - Brunelli, Danny
AU - Callura, Giulia
AU - Calzolari, Michela
AU - La Placa, Silvia
AU - Lo Re, Emanuele
AU - Pettinati, Francesca
AU - Piana, Annamaria
AU - Regaldo, Marzia
AU - Henriquet, Franco
AU - Davoodi, Iraj
AU - Gallucci, Michele
AU - Roy, Maria Teresa
AU - Tranchida, Tamara
AU - Roccatagliata, Camilla
AU - Vignali, Stefano
AU - Giordano, Monica
AU - Salvini, Elias
AU - Vignolo, Luana
AU - Giordo, Giulia
AU - Romeo, Valentina
AU - Guillen, Marco
AU - Borrazzo, Alessandro
AU - Marenco, Silvia
AU - Camporeale, Margherita
AU - Bissiri, Rina
AU - Zavaglia, Patrizia
AU - Grifasi, Cinzia
AU - Massidda, Immacolata
N1 - Publisher Copyright:
© 2021 The Authors
PY - 2021/6
Y1 - 2021/6
N2 - Purpose: Unmet needs for advanced-disease cancer patients are fatigue, pain, and emotional support. Little information is available about the feasibility of interventions focused on patient-reported outcome measurement developed according to the Medical Research Council (MRC) Framework in advanced-disease cancer patients. We aimed to pilot a nurse-led complex intervention focused on QoL assessment in advanced-disease cancer patients. Methods: The INFO-QoL study was based on an exploratory, nonequivalent comparison group, pre-test-post-test design. Study sites received either the INFO-QoL intervention or usual care. Adult advanced-disease cancer patients admitted to hospice inpatient units that gave their informed consent were included in the study. Subjects were 187 patients and their families and 19 healthcare professionals. We evaluated feasibility, acceptability, and patients' outcomes using the Integrated Palliative Care Outcome Scale. Results: Nineteen healthcare professionals were included. The mean competence score increased significantly over time (p < 0.001) and the mean usefulness score was high 8.63 (±1.36). In the post-test phase, 54 patients were allocated to the experimental unit and 36 in the comparison unit. Compared to the comparison unit, in the experimental unit anxiety (R2 = 0.07; 95% CI = −0.06; 0.19), family anxiety (R2 = 0.22; 95% CI = −0.03; 0.41), depression (R2 = 0.31; 95% CI = −0.05; 0.56) and sharing feelings (R2 = 0.09; 95% CI = −0.05; 0.23), were improved between pre-test and post-test phase. Conclusions: The INFO-QoL was feasible and potentially improved psychological outcomes. Despite the high attrition rate, the INFO-QoL improved the quality and safety culture for patients in palliative care settings.
AB - Purpose: Unmet needs for advanced-disease cancer patients are fatigue, pain, and emotional support. Little information is available about the feasibility of interventions focused on patient-reported outcome measurement developed according to the Medical Research Council (MRC) Framework in advanced-disease cancer patients. We aimed to pilot a nurse-led complex intervention focused on QoL assessment in advanced-disease cancer patients. Methods: The INFO-QoL study was based on an exploratory, nonequivalent comparison group, pre-test-post-test design. Study sites received either the INFO-QoL intervention or usual care. Adult advanced-disease cancer patients admitted to hospice inpatient units that gave their informed consent were included in the study. Subjects were 187 patients and their families and 19 healthcare professionals. We evaluated feasibility, acceptability, and patients' outcomes using the Integrated Palliative Care Outcome Scale. Results: Nineteen healthcare professionals were included. The mean competence score increased significantly over time (p < 0.001) and the mean usefulness score was high 8.63 (±1.36). In the post-test phase, 54 patients were allocated to the experimental unit and 36 in the comparison unit. Compared to the comparison unit, in the experimental unit anxiety (R2 = 0.07; 95% CI = −0.06; 0.19), family anxiety (R2 = 0.22; 95% CI = −0.03; 0.41), depression (R2 = 0.31; 95% CI = −0.05; 0.56) and sharing feelings (R2 = 0.09; 95% CI = −0.05; 0.23), were improved between pre-test and post-test phase. Conclusions: The INFO-QoL was feasible and potentially improved psychological outcomes. Despite the high attrition rate, the INFO-QoL improved the quality and safety culture for patients in palliative care settings.
KW - Advance care planning
KW - Complex interventions
KW - Hospice and palliative care nursing
KW - Implementation science
KW - Palliative care
KW - Patient reported outcome measures
KW - Quality of life
UR - http://www.scopus.com/inward/record.url?scp=85105442796&partnerID=8YFLogxK
U2 - 10.1016/j.ejon.2021.101961
DO - 10.1016/j.ejon.2021.101961
M3 - Article
SN - 1462-3889
VL - 52
JO - European Journal of Oncology Nursing
JF - European Journal of Oncology Nursing
M1 - 101961
ER -
