Proteomic analysis of peritoneal fluid in women with endometriosis

Simone Ferrero; David J. Gillott; Valentino Remorgida; Paola Anserini; Kit Yi Leung; Nicola Ragni; Jurgis G. Grudzinskas

doi:10.1021/pr060680q

Proteomic analysis of peritoneal fluid in women with endometriosis

Simone Ferrero, David J. Gillott, Valentino Remorgida, Paola Anserini, Kit Yi Leung, Nicola Ragni, Jurgis G. Grudzinskas

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

This study aims to evaluate differences in the expression of proteins present in the peritoneal fluid (PF) of women with and without endometriosis. PF samples were subjected to two-dimensional gel electrophoresis; protein spots of interest were identified by liquid chromatography tandem mass spectrometry. Several molecules had aberrant expression in PF of women with endometriosis; they may be useful for a better understanding of the pathogenesis of this disease.

Lingua originale	Inglese
pagine (da-a)	3402-3411
Numero di pagine	10
Rivista	Journal of Proteome Research
Volume	6
Numero di pubblicazione	9
DOI	https://doi.org/10.1021/pr060680q
Stato di pubblicazione	Pubblicato - set 2007
Pubblicato esternamente	Sì

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10.1021/pr060680q

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abstract = "This study aims to evaluate differences in the expression of proteins present in the peritoneal fluid (PF) of women with and without endometriosis. PF samples were subjected to two-dimensional gel electrophoresis; protein spots of interest were identified by liquid chromatography tandem mass spectrometry. Several molecules had aberrant expression in PF of women with endometriosis; they may be useful for a better understanding of the pathogenesis of this disease.",

keywords = "Endometriosis, Peritoneal fluid, Proteomics, Tandem mass spectrometry, Two-dimensional gel electrophoresis",

author = "Simone Ferrero and Gillott, {David J.} and Valentino Remorgida and Paola Anserini and Leung, {Kit Yi} and Nicola Ragni and Grudzinskas, {Jurgis G.}",

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AU - Ferrero, Simone

AU - Gillott, David J.

AU - Remorgida, Valentino

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AU - Leung, Kit Yi

AU - Ragni, Nicola

AU - Grudzinskas, Jurgis G.

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AB - This study aims to evaluate differences in the expression of proteins present in the peritoneal fluid (PF) of women with and without endometriosis. PF samples were subjected to two-dimensional gel electrophoresis; protein spots of interest were identified by liquid chromatography tandem mass spectrometry. Several molecules had aberrant expression in PF of women with endometriosis; they may be useful for a better understanding of the pathogenesis of this disease.

KW - Endometriosis

KW - Peritoneal fluid

KW - Proteomics

KW - Tandem mass spectrometry

KW - Two-dimensional gel electrophoresis

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Proteomic analysis of peritoneal fluid in women with endometriosis

Abstract

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