Polyurethane-based biomaterials for shape-adjustable cardiovascular devices

A. Silvestri; P. M. Serafini; S. Sartori; P. Ferrando; F. Boccafoschi; S. Milione; L. Conzatti; G. Ciardelli

doi:10.1002/app.34779

Polyurethane-based biomaterials for shape-adjustable cardiovascular devices

A. Silvestri, P. M. Serafini, S. Sartori, P. Ferrando, F. Boccafoschi, S. Milione, L. Conzatti, G. Ciardelli

Dipartimento di Scienze della Salute

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

A series of biostable polyurethane (PUR) formulations, including a composite containing a clay as filler, were prepared as new biomaterials for cardiovascular applications. Poly(dimethyl siloxane) and poly(tetramethylene oxide) were selected as macrodiols because of their mechanical properties and the high hydrolysis resistance they confer to PURs. 1,6-Diisocyanatohexane and 1,4-cyclohexane dimethanol were used as a diisocyanate and chain extender, respectively. The polymeric products were chemically, thermally, and mechanically characterized. Thermomechanical characterizations highlighted that some of the obtained formulations are promising materials for applications in the cardiovascular field, in particular, for the realization of annuloplastic rings in mitral valve repair.

Lingua originale	Inglese
pagine (da-a)	3661-3671
Numero di pagine	11
Rivista	Journal of Applied Polymer Science
Volume	122
Numero di pubblicazione	6
DOI	https://doi.org/10.1002/app.34779
Stato di pubblicazione	Pubblicato - 15 dic 2011

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10.1002/app.34779

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abstract = "A series of biostable polyurethane (PUR) formulations, including a composite containing a clay as filler, were prepared as new biomaterials for cardiovascular applications. Poly(dimethyl siloxane) and poly(tetramethylene oxide) were selected as macrodiols because of their mechanical properties and the high hydrolysis resistance they confer to PURs. 1,6-Diisocyanatohexane and 1,4-cyclohexane dimethanol were used as a diisocyanate and chain extender, respectively. The polymeric products were chemically, thermally, and mechanically characterized. Thermomechanical characterizations highlighted that some of the obtained formulations are promising materials for applications in the cardiovascular field, in particular, for the realization of annuloplastic rings in mitral valve repair.",

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AU - Silvestri, A.

AU - Serafini, P. M.

AU - Sartori, S.

AU - Ferrando, P.

AU - Boccafoschi, F.

AU - Milione, S.

AU - Conzatti, L.

AU - Ciardelli, G.

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Polyurethane-based biomaterials for shape-adjustable cardiovascular devices

Abstract

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