TY - JOUR
T1 - Polysaccharide-based hydrogels containing herbal extracts for wound healing applications
AU - Abazari, Morteza
AU - Akbari, Tayebeh
AU - Hasani, Mahdiye
AU - Sharifikolouei, Elham
AU - Raoufi, Mohammad
AU - Foroumadi, Alireza
AU - Sharifzadeh, Mohammad
AU - Firoozpour, Loghman
AU - Khoobi, Mehdi
N1 - Publisher Copyright:
© 2022 Elsevier Ltd
PY - 2022/10/15
Y1 - 2022/10/15
N2 - Development of an ideal wound dressing with effective function for healing various types of wounds is the ultimate desire of the researchers. Natural-based compounds such as polysaccharides and phytochemicals offer useful properties making them perfect candidates for wound management. Polysaccharides-based hydrogels with an interconnected three-dimensional network, and desired properties have great potential as a carrier for delivery of different herbal extracts for oral and topical applications. Herbal extracts are extensively used for wound healing purposes, individually or in combination with other active agents. This study summarizes the current knowledge acquired on the preparation, functionalizing, and application of different kinds of polysaccharide-based hydrogels enriched by herbal extracts for different wound healing applications. The structural, biological, and functional impact of the polysaccharides and herbal extracts on the final hydrogel characteristics, as well as their influence on the different phases of the wound healing process have been discussed.
AB - Development of an ideal wound dressing with effective function for healing various types of wounds is the ultimate desire of the researchers. Natural-based compounds such as polysaccharides and phytochemicals offer useful properties making them perfect candidates for wound management. Polysaccharides-based hydrogels with an interconnected three-dimensional network, and desired properties have great potential as a carrier for delivery of different herbal extracts for oral and topical applications. Herbal extracts are extensively used for wound healing purposes, individually or in combination with other active agents. This study summarizes the current knowledge acquired on the preparation, functionalizing, and application of different kinds of polysaccharide-based hydrogels enriched by herbal extracts for different wound healing applications. The structural, biological, and functional impact of the polysaccharides and herbal extracts on the final hydrogel characteristics, as well as their influence on the different phases of the wound healing process have been discussed.
KW - Herbal extracts
KW - Polysaccharide-based hydrogel
KW - Wound healing phases
UR - https://www.scopus.com/pages/publications/85133469953
U2 - 10.1016/j.carbpol.2022.119808
DO - 10.1016/j.carbpol.2022.119808
M3 - Review article
SN - 0144-8617
VL - 294
JO - Carbohydrate Polymers
JF - Carbohydrate Polymers
M1 - 119808
ER -