Paramagnetic solid lipid nanoparticles as a novel platform for the development of molecular MRI probes

Gabriele A. Rolla; Mauro Botta; Lorenzo Tei; Claudia Cabella; Simona Ghiani; Chiara Brioschi; Alessandro Maiocchi

doi:10.1002/chem.201301837

Paramagnetic solid lipid nanoparticles as a novel platform for the development of molecular MRI probes

Gabriele A. Rolla
, Mauro Botta
, Lorenzo Tei
, Claudia Cabella
, Simona Ghiani
, Chiara Brioschi
, Alessandro Maiocchi

Dipartimento di Scienze e Innovazione Tecnologica

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

Highly efficient magnetic resonance imaging (MRI) probes have been prepared by loading Gd^III complexes on the surface of solid lipid nanoparticles (pSLNs). Applicability as molecular imaging probes is demonstrated by an in vitro model study with targeted pSLNs.

Lingua originale	Inglese
pagine (da-a)	11189-11193
Numero di pagine	5
Rivista	Chemistry - A European Journal
Volume	19
Numero di pubblicazione	34
DOI	https://doi.org/10.1002/chem.201301837
Stato di pubblicazione	Pubblicato - 19 ago 2013

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10.1002/chem.201301837

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title = "Paramagnetic solid lipid nanoparticles as a novel platform for the development of molecular MRI probes",

abstract = "Highly efficient magnetic resonance imaging (MRI) probes have been prepared by loading GdIII complexes on the surface of solid lipid nanoparticles (pSLNs). Applicability as molecular imaging probes is demonstrated by an in vitro model study with targeted pSLNs.",

keywords = "contrast agents, lanthanides, lipidic nanoparticles, magnetic resonance imaging, relaxivity",

author = "Rolla, \{Gabriele A.\} and Mauro Botta and Lorenzo Tei and Claudia Cabella and Simona Ghiani and Chiara Brioschi and Alessandro Maiocchi",

year = "2013",

month = aug,

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AU - Rolla, Gabriele A.

AU - Botta, Mauro

AU - Tei, Lorenzo

AU - Cabella, Claudia

AU - Ghiani, Simona

AU - Brioschi, Chiara

AU - Maiocchi, Alessandro

PY - 2013/8/19

Y1 - 2013/8/19

N2 - Highly efficient magnetic resonance imaging (MRI) probes have been prepared by loading GdIII complexes on the surface of solid lipid nanoparticles (pSLNs). Applicability as molecular imaging probes is demonstrated by an in vitro model study with targeted pSLNs.

AB - Highly efficient magnetic resonance imaging (MRI) probes have been prepared by loading GdIII complexes on the surface of solid lipid nanoparticles (pSLNs). Applicability as molecular imaging probes is demonstrated by an in vitro model study with targeted pSLNs.

KW - contrast agents

KW - lanthanides

KW - lipidic nanoparticles

KW - magnetic resonance imaging

KW - relaxivity

UR - https://www.scopus.com/pages/publications/84882250985

U2 - 10.1002/chem.201301837

DO - 10.1002/chem.201301837

M3 - Article

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JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

IS - 34

ER -

Paramagnetic solid lipid nanoparticles as a novel platform for the development of molecular MRI probes

Abstract

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