On the compatibility criteria for protein encapsulation inside mesoporous materials

Lara Giussani; Ettore Fois; Enrica Gianotti; Gloria Tabacchi; Aldo Gamba; Salvatore Coluccia

doi:10.1002/cphc.200901038

On the compatibility criteria for protein encapsulation inside mesoporous materials

Lara Giussani, Ettore Fois, Enrica Gianotti, Gloria Tabacchi, Aldo Gamba, Salvatore Coluccia

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

The properties of the enzyme pepsin, relevant to its incorporation inside the channels of mesoporous silica materials in the preparation of bioinorganic hybrids, are highlighted by molecular dynamics simulations of aqueous solutions of the protein under conditions optimal for encapsulation in SBA-15. The protein size, shape, flexibility and surface properties are calculated with the aim of deriving general accessibility/compatibility criteria favouring encapsulation inside mesoporous systems.

Lingua originale	Inglese
pagine (da-a)	1757-1762
Numero di pagine	6
Rivista	ChemPhysChem
Volume	11
Numero di pubblicazione	8
DOI	https://doi.org/10.1002/cphc.200901038
Stato di pubblicazione	Pubblicato - 7 giu 2010
Pubblicato esternamente	Sì

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10.1002/cphc.200901038

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title = "On the compatibility criteria for protein encapsulation inside mesoporous materials",

abstract = "The properties of the enzyme pepsin, relevant to its incorporation inside the channels of mesoporous silica materials in the preparation of bioinorganic hybrids, are highlighted by molecular dynamics simulations of aqueous solutions of the protein under conditions optimal for encapsulation in SBA-15. The protein size, shape, flexibility and surface properties are calculated with the aim of deriving general accessibility/compatibility criteria favouring encapsulation inside mesoporous systems.",

keywords = "Bioinorganic chemistry, Enzyme models, Molecular dynamics, Organic-inorganic hybrid composites, Pepsin",

author = "Lara Giussani and Ettore Fois and Enrica Gianotti and Gloria Tabacchi and Aldo Gamba and Salvatore Coluccia",

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AU - Fois, Ettore

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AU - Gamba, Aldo

AU - Coluccia, Salvatore

PY - 2010/6/7

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KW - Enzyme models

KW - Molecular dynamics

KW - Organic-inorganic hybrid composites

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On the compatibility criteria for protein encapsulation inside mesoporous materials

Abstract

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