Abstract
The conformational space of the tetrasaccharide α‐L‐Fuc‐(1→2)‐β‐D‐Gal‐(1→3)‐β‐D‐GalNAc‐(1→3)‐α‐D‐GallPr (3) and of some overlapping di‐ and trisaccharide sequences was investigated with the aid of molecular‐mechanics energy minimizations, molecular‐dynamics simulations, and 1H‐NMR analysis. These investigations suggested that in compound 3 a certain rigidity of the first two glycosidic linkages (Fuc‐Gal and Gal‐GalNAc) is combined with the flexibility of the third one (GalNAc‐Gal).
Lingua originale | Inglese |
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pagine (da-a) | 636-646 |
Numero di pagine | 11 |
Rivista | Helvetica Chimica Acta |
Volume | 78 |
Numero di pubblicazione | 3 |
DOI | |
Stato di pubblicazione | Pubblicato - 10 mag 1995 |
Pubblicato esternamente | Sì |