TY - JOUR
T1 - Nutritional assessment and medical dietary therapy for management of obesity in patients with non-dialysis chronic kidney disease
T2 - a practical guide for endocrinologist, nutritionists and nephrologists. A consensus statement from the Italian society of endocrinology (SIE), working group of the club nutrition–hormones and metabolism; the Italian society of nutraceuticals (SINut), club ketodiets and nutraceuticals “KetoNut-SINut”; and the Italian society of nephrology (SIN)
AU - Annunziata, G.
AU - Caprio, M.
AU - Verde, L.
AU - Carella, A. M.
AU - Camajani, E.
AU - Benvenuto, A.
AU - Paolini, B.
AU - De Nicola, L.
AU - Aucella, F.
AU - Bellizzi, V.
AU - Barberi, S.
AU - Grassi, D.
AU - Fogacci, F.
AU - Colao, A.
AU - Cicero, A. F.G.
AU - Prodam, F.
AU - Aimaretti, G.
AU - Muscogiuri, G.
AU - Barrea, L.
N1 - Publisher Copyright:
© The Author(s), under exclusive licence to Italian Society of Endocrinology (SIE) 2024.
PY - 2024/12
Y1 - 2024/12
N2 - Purpose: Chronic kidney disease (CKD) is a serious health concern with an estimated prevalence of about 13.4% worldwide. It is cause and consequence of various comorbidities, including cardiovascular diseases. In parallel, common pathological conditions closely related to ageing and unhealthy dietary habits increase the risk of CKD development and progression, including type 2 diabetes and obesity. Among these, obesity is either independent risk factor for new onset kidney disease or accelerates the rate of decline of kidney function by multiple mechanisms. Therefore, the role of diets aimed at attaining weight loss in patients with obesity is clearly essential to prevent CKD as to slow disease progression. Various dietary approaches have been licensed for the medical dietary therapy in CKD, including low-protein diet and Mediterranean diet. Interestingly, emerging evidence also support the use of low-carbohydrate/ketogenic diet (LCD/KD) in these patients. More specifically, LCD/KDs may efficiently promote weight loss, improve metabolic parameters, and reduce inflammation and oxidative stress, resulting in a dietary strategy that act globally in managing collateral conditions that are directly and indirectly related to the kidney function. Conclusion: This consensus statement from the Italian Society of Endocrinology (SIE), working group of the Club Nutrition – Hormones and Metabolism; the Italian Society of Nutraceuticals (SINut), Club Ketodiets and Nutraceuticals “KetoNut-SINut”; and the Italian Society of Nephrology (SIN) is intended to be a guide for Endocrinologist, Nutritionists and Nephrologist who deal with the management of patients with obesity with non-dialysis CKD providing a practical guidance on assessing nutritional status and prescribing the optimal diet in order to best manage obesity to prevent CKD and its progression to dialysis. Graphical abstract: (Figure presented.)
AB - Purpose: Chronic kidney disease (CKD) is a serious health concern with an estimated prevalence of about 13.4% worldwide. It is cause and consequence of various comorbidities, including cardiovascular diseases. In parallel, common pathological conditions closely related to ageing and unhealthy dietary habits increase the risk of CKD development and progression, including type 2 diabetes and obesity. Among these, obesity is either independent risk factor for new onset kidney disease or accelerates the rate of decline of kidney function by multiple mechanisms. Therefore, the role of diets aimed at attaining weight loss in patients with obesity is clearly essential to prevent CKD as to slow disease progression. Various dietary approaches have been licensed for the medical dietary therapy in CKD, including low-protein diet and Mediterranean diet. Interestingly, emerging evidence also support the use of low-carbohydrate/ketogenic diet (LCD/KD) in these patients. More specifically, LCD/KDs may efficiently promote weight loss, improve metabolic parameters, and reduce inflammation and oxidative stress, resulting in a dietary strategy that act globally in managing collateral conditions that are directly and indirectly related to the kidney function. Conclusion: This consensus statement from the Italian Society of Endocrinology (SIE), working group of the Club Nutrition – Hormones and Metabolism; the Italian Society of Nutraceuticals (SINut), Club Ketodiets and Nutraceuticals “KetoNut-SINut”; and the Italian Society of Nephrology (SIN) is intended to be a guide for Endocrinologist, Nutritionists and Nephrologist who deal with the management of patients with obesity with non-dialysis CKD providing a practical guidance on assessing nutritional status and prescribing the optimal diet in order to best manage obesity to prevent CKD and its progression to dialysis. Graphical abstract: (Figure presented.)
KW - Bioelectrical impedance analysis
KW - Chronic kidney disease
KW - Diet
KW - Ketogenic diet
KW - Mediterranean diet
KW - Nutrition
KW - Nutritional management
KW - Obesity
UR - https://www.scopus.com/pages/publications/85204392518
U2 - 10.1007/s40618-024-02446-8
DO - 10.1007/s40618-024-02446-8
M3 - Article
SN - 0391-4097
VL - 47
SP - 2889
EP - 2913
JO - Journal of Endocrinological Investigation
JF - Journal of Endocrinological Investigation
IS - 12
ER -
