Nuclear Magnetic Relaxation dispersion profiles of substantia nigra pars compacta in Parkinson's disease patients are consistent with protein aggregation

Leonardo Lopiano; Mauro Fasano; Sabrina Giraudo; Giuseppe Digilio; Seymour H. Koenig; Elena Torre; Bruno Bergamasco; Silvio Aime

doi:10.1016/S0197-0186(00)00036-X

Nuclear Magnetic Relaxation dispersion profiles of substantia nigra pars compacta in Parkinson's disease patients are consistent with protein aggregation

Leonardo Lopiano
, Mauro Fasano
, Sabrina Giraudo
, Giuseppe Digilio
, Seymour H. Koenig
, Elena Torre
, Bruno Bergamasco
, Silvio Aime

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

Nuclear Magnetic Relaxation field-cycling relaxometry is a technique, able to report on water mobility in tissues. By means of this technique, post-mortem specimens from both controls and idiopathic Parkinson's disease patients have been investigated. Results show different relaxometric behavior between the groups, which is consistent with protein aggregation in Parkinson's disease specimens. Copyright (C) 2000 Elsevier Science Ltd.

Lingua originale	Inglese
pagine (da-a)	331-336
Numero di pagine	6
Rivista	Neurochemistry International
Volume	37
Numero di pubblicazione	4
DOI	https://doi.org/10.1016/S0197-0186(00)00036-X
Stato di pubblicazione	Pubblicato - 1 ott 2000
Pubblicato esternamente	Sì

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10.1016/S0197-0186(00)00036-X

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title = "Nuclear Magnetic Relaxation dispersion profiles of substantia nigra pars compacta in Parkinson's disease patients are consistent with protein aggregation",

abstract = "Nuclear Magnetic Relaxation field-cycling relaxometry is a technique, able to report on water mobility in tissues. By means of this technique, post-mortem specimens from both controls and idiopathic Parkinson's disease patients have been investigated. Results show different relaxometric behavior between the groups, which is consistent with protein aggregation in Parkinson's disease specimens. Copyright (C) 2000 Elsevier Science Ltd.",

author = "Leonardo Lopiano and Mauro Fasano and Sabrina Giraudo and Giuseppe Digilio and Koenig, \{Seymour H.\} and Elena Torre and Bruno Bergamasco and Silvio Aime",

note = "Funding Information: S. G. thanks the Italian Parkinson{\textquoteright}s Association (AIP) for a postdoctoral fellowship. The authors acknowledge the Nederlandse Hersenbank, Amsterdam, for supplying pathological tissue specimens and control group. ",

year = "2000",

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doi = "10.1016/S0197-0186(00)00036-X",

language = "English",

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Nuclear Magnetic Relaxation dispersion profiles of substantia nigra pars compacta in Parkinson's disease patients are consistent with protein aggregation. / Lopiano, Leonardo; Fasano, Mauro; Giraudo, Sabrina et al.
In: Neurochemistry International, Vol. 37, N. 4, 01.10.2000, pag. 331-336.

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

TY - JOUR

T1 - Nuclear Magnetic Relaxation dispersion profiles of substantia nigra pars compacta in Parkinson's disease patients are consistent with protein aggregation

AU - Lopiano, Leonardo

AU - Fasano, Mauro

AU - Giraudo, Sabrina

AU - Digilio, Giuseppe

AU - Koenig, Seymour H.

AU - Torre, Elena

AU - Bergamasco, Bruno

AU - Aime, Silvio

N1 - Funding Information: S. G. thanks the Italian Parkinson’s Association (AIP) for a postdoctoral fellowship. The authors acknowledge the Nederlandse Hersenbank, Amsterdam, for supplying pathological tissue specimens and control group.

PY - 2000/10/1

Y1 - 2000/10/1

N2 - Nuclear Magnetic Relaxation field-cycling relaxometry is a technique, able to report on water mobility in tissues. By means of this technique, post-mortem specimens from both controls and idiopathic Parkinson's disease patients have been investigated. Results show different relaxometric behavior between the groups, which is consistent with protein aggregation in Parkinson's disease specimens. Copyright (C) 2000 Elsevier Science Ltd.

AB - Nuclear Magnetic Relaxation field-cycling relaxometry is a technique, able to report on water mobility in tissues. By means of this technique, post-mortem specimens from both controls and idiopathic Parkinson's disease patients have been investigated. Results show different relaxometric behavior between the groups, which is consistent with protein aggregation in Parkinson's disease specimens. Copyright (C) 2000 Elsevier Science Ltd.

UR - https://www.scopus.com/pages/publications/0034309848

U2 - 10.1016/S0197-0186(00)00036-X

DO - 10.1016/S0197-0186(00)00036-X

M3 - Article

SN - 0197-0186

VL - 37

SP - 331

EP - 336

JO - Neurochemistry International

JF - Neurochemistry International

IS - 4

ER -

Nuclear Magnetic Relaxation dispersion profiles of substantia nigra pars compacta in Parkinson's disease patients are consistent with protein aggregation

Abstract

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