Novel functionalized pyridine-containing DTPA-like ligand. Synthesis, computational studies and characterization of the corresponding GdIII complex

Roberto Artali; Mauro Botta; Camilla Cavallotti; Giovanni B. Giovenzana; Giovanni Palmisano; Massimo Sisti

doi:10.1039/b706236b

Novel functionalized pyridine-containing DTPA-like ligand. Synthesis, computational studies and characterization of the corresponding Gd^III complex

Roberto Artali
, Mauro Botta
, Camilla Cavallotti
, Giovanni B. Giovenzana
, Giovanni Palmisano
, Massimo Sisti

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

A novel pyridine-containing DTPA-like ligand, carrying additional hydroxymethyl groups on the pyridine side-arms, was synthesized in 5 steps. The corresponding Gd^III complex, potentially useful as an MRI contrast agent, was prepared and characterized in detail by relaxometric methods and its structure modeled by computational methods.

Lingua originale	Inglese
pagine (da-a)	2441-2447
Numero di pagine	7
Rivista	Organic and Biomolecular Chemistry
Volume	5
Numero di pubblicazione	15
DOI	https://doi.org/10.1039/b706236b
Stato di pubblicazione	Pubblicato - 2007

Accesso al documento

10.1039/b706236b

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title = "Novel functionalized pyridine-containing DTPA-like ligand. Synthesis, computational studies and characterization of the corresponding GdIII complex",

abstract = "A novel pyridine-containing DTPA-like ligand, carrying additional hydroxymethyl groups on the pyridine side-arms, was synthesized in 5 steps. The corresponding GdIII complex, potentially useful as an MRI contrast agent, was prepared and characterized in detail by relaxometric methods and its structure modeled by computational methods.",

author = "Roberto Artali and Mauro Botta and Camilla Cavallotti and Giovenzana, \{Giovanni B.\} and Giovanni Palmisano and Massimo Sisti",

year = "2007",

doi = "10.1039/b706236b",

language = "English",

volume = "5",

pages = "2441--2447",

journal = "Organic and Biomolecular Chemistry",

issn = "1477-0520",

publisher = "Royal Society of Chemistry",

number = "15",

}

Novel functionalized pyridine-containing DTPA-like ligand. Synthesis, computational studies and characterization of the corresponding Gd^III complex. / Artali, Roberto; Botta, Mauro; Cavallotti, Camilla et al.
In: Organic and Biomolecular Chemistry, Vol. 5, N. 15, 2007, pag. 2441-2447.

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

TY - JOUR

T1 - Novel functionalized pyridine-containing DTPA-like ligand. Synthesis, computational studies and characterization of the corresponding GdIII complex

AU - Artali, Roberto

AU - Botta, Mauro

AU - Cavallotti, Camilla

AU - Giovenzana, Giovanni B.

AU - Palmisano, Giovanni

AU - Sisti, Massimo

PY - 2007

Y1 - 2007

N2 - A novel pyridine-containing DTPA-like ligand, carrying additional hydroxymethyl groups on the pyridine side-arms, was synthesized in 5 steps. The corresponding GdIII complex, potentially useful as an MRI contrast agent, was prepared and characterized in detail by relaxometric methods and its structure modeled by computational methods.

AB - A novel pyridine-containing DTPA-like ligand, carrying additional hydroxymethyl groups on the pyridine side-arms, was synthesized in 5 steps. The corresponding GdIII complex, potentially useful as an MRI contrast agent, was prepared and characterized in detail by relaxometric methods and its structure modeled by computational methods.

UR - https://www.scopus.com/pages/publications/34547232151

U2 - 10.1039/b706236b

DO - 10.1039/b706236b

M3 - Article

SN - 1477-0520

VL - 5

SP - 2441

EP - 2447

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 15