Abstract
New three-dimensional structures of allosteric proteins reveal they have a flexible architecture that is instrumental to the regulation of protein function. Highlights are the structures of GroEL, pyruvate kinase, D-9-phosphoglycerate dehydrogenase and the acetylcholine receptor. Furthermore, significant progress in understanding the nature of the intermediates involved in an allosteric reaction has been achieved through recent spectroscopic and crystallographic studies on haemoglobin.
Lingua originale | Inglese |
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pagine (da-a) | 824-829 |
Numero di pagine | 6 |
Rivista | Current Opinion in Structural Biology |
Volume | 6 |
Numero di pubblicazione | 6 |
DOI | |
Stato di pubblicazione | Pubblicato - dic 1996 |
Pubblicato esternamente | Sì |