Narrow-band ultraviolet b phototherapy in psoriasis reduces pro-inflammatory cytokine levels and improves vitiligo and neutrophilic asthma

Psoriasis, neutrophilic asthma, and vitiligo vulgaris are three immune-mediated diseases in which raised serum levels of pro-inflammatory T helper (Th) 1/Th17 cytokines have been detected. Psoriasis is considered a systemic disease with several comorbidities and the role of high levels of cytokines referable to Th1-Th17 patterns in the pathogenesis of these comorbidities remains to be clarified (1-3). Two monozygotic twins of 69 years old affected by psoriasis and vitiligo were referred to the outpatient clinic of our Internal Medicine Department, because of poorly controlled asthma. Both twins had asthma that was treated with montelukast 10 mg a day, inhaled corticosteroid and long-acting β2 agonist (fluticasone / formeterol 250/10 mcg) twice daily during the last six months. This article is protected by copyright. All rights reserved.