Muscarinic cholinergic receptor binding in rat mast cells

E. Masini; R. Fantozzi; P. Blandina; S. Brunelleschi; P. F. Mannaioni

doi:10.1007/BF01971484

Muscarinic cholinergic receptor binding in rat mast cells

E. Masini
, R. Fantozzi
, P. Blandina
, S. Brunelleschi
, P. F. Mannaioni

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

Specific [³H]-QNB binding was present in isolated, purified, intact rat mast cells and in crude membrane preparations. The binding is saturable, time- and temperature-dependent. Cholinergic agents inhibit selectively the binding: atropine is the most effective of the antagonists while oxotremorine is the most potent of the muscarinic agonists. It is concluded that rat mast cells are provided with muscarinic cholinergic receptors.

Lingua originale	Inglese
pagine (da-a)	327-332
Numero di pagine	6
Rivista	Agents and Actions
Volume	13
Numero di pubblicazione	4
DOI	https://doi.org/10.1007/BF01971484
Stato di pubblicazione	Pubblicato - lug 1983
Pubblicato esternamente	Sì

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10.1007/BF01971484

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title = "Muscarinic cholinergic receptor binding in rat mast cells",

abstract = "Specific [3H]-QNB binding was present in isolated, purified, intact rat mast cells and in crude membrane preparations. The binding is saturable, time- and temperature-dependent. Cholinergic agents inhibit selectively the binding: atropine is the most effective of the antagonists while oxotremorine is the most potent of the muscarinic agonists. It is concluded that rat mast cells are provided with muscarinic cholinergic receptors.",

author = "E. Masini and R. Fantozzi and P. Blandina and S. Brunelleschi and Mannaioni, \{P. F.\}",

year = "1983",

month = jul,

doi = "10.1007/BF01971484",

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T1 - Muscarinic cholinergic receptor binding in rat mast cells

AU - Masini, E.

AU - Fantozzi, R.

AU - Blandina, P.

AU - Brunelleschi, S.

AU - Mannaioni, P. F.

PY - 1983/7

Y1 - 1983/7

N2 - Specific [3H]-QNB binding was present in isolated, purified, intact rat mast cells and in crude membrane preparations. The binding is saturable, time- and temperature-dependent. Cholinergic agents inhibit selectively the binding: atropine is the most effective of the antagonists while oxotremorine is the most potent of the muscarinic agonists. It is concluded that rat mast cells are provided with muscarinic cholinergic receptors.

AB - Specific [3H]-QNB binding was present in isolated, purified, intact rat mast cells and in crude membrane preparations. The binding is saturable, time- and temperature-dependent. Cholinergic agents inhibit selectively the binding: atropine is the most effective of the antagonists while oxotremorine is the most potent of the muscarinic agonists. It is concluded that rat mast cells are provided with muscarinic cholinergic receptors.

UR - https://www.scopus.com/pages/publications/0020629751

U2 - 10.1007/BF01971484

DO - 10.1007/BF01971484

M3 - Article

SN - 0065-4299

VL - 13

SP - 327

EP - 332

JO - Agents and Actions

JF - Agents and Actions

IS - 4

ER -

Muscarinic cholinergic receptor binding in rat mast cells

Abstract

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