TY - JOUR
T1 - Mortality study on a cohort of Italian licensed pesticide users
AU - Torchio, Pierfederico
AU - Lepore, Anna Raffella
AU - Corrao, Giovanni
AU - Comba, Pietro
AU - Settimi, Laura
AU - Belli, Stefano
AU - Magnani, Corrado
AU - di Orio, Ferdinando
N1 - Funding Information:
Even though farmers are usually considered a low risk category for most diseases, various epide- * Corresponding author, Centro lnterdipartimentale di Epidemiologia, Via Verdi, 28, 67 100 L'Aquila, Italy. $This work was supported by grants from the Consiglio Nazionale delle Ricerche (CNR) and by the Piedmont Region.
PY - 1994/6/20
Y1 - 1994/6/20
N2 - This study describes the mortality experience in a cohort of 23 401 farmers, residing in southern Piedmont, Italy, and licensed to use pesticides. From 1970 to 1986 the cohort included 340 794 person-years and 2683 deaths were observed. A strong attenuation of the death risk was found due to the healthy worker effect (seen as an active role in the application for the license by the members of the cohort) and due to the limited comparability of the cohort with respect to the reference population. The standardized mortality ratios (SMRs) were remarkably < 100 for all causes (SMR = 59; 95% confidence interval = 57-61) and for all tumors (SMR = 60; 95% CI 55-64), but they increased with the increasing duration of the follow-up. A risk increase was observed with respect to melanomas and eye tumors in the entire cohort and lymphoma and tumors of the connective tissue in the subcohort of subjects living in villages with mainly arable land.
AB - This study describes the mortality experience in a cohort of 23 401 farmers, residing in southern Piedmont, Italy, and licensed to use pesticides. From 1970 to 1986 the cohort included 340 794 person-years and 2683 deaths were observed. A strong attenuation of the death risk was found due to the healthy worker effect (seen as an active role in the application for the license by the members of the cohort) and due to the limited comparability of the cohort with respect to the reference population. The standardized mortality ratios (SMRs) were remarkably < 100 for all causes (SMR = 59; 95% confidence interval = 57-61) and for all tumors (SMR = 60; 95% CI 55-64), but they increased with the increasing duration of the follow-up. A risk increase was observed with respect to melanomas and eye tumors in the entire cohort and lymphoma and tumors of the connective tissue in the subcohort of subjects living in villages with mainly arable land.
KW - Cohort study
KW - Occupational exposure
UR - http://www.scopus.com/inward/record.url?scp=0028158973&partnerID=8YFLogxK
U2 - 10.1016/0048-9697(94)90178-3
DO - 10.1016/0048-9697(94)90178-3
M3 - Article
SN - 0048-9697
VL - 149
SP - 183
EP - 191
JO - Science of the Total Environment
JF - Science of the Total Environment
IS - 3
ER -