Mortality of parents of children with cancer: A population-based study in Turin, Italy

Maria Luisa Mosso, Corrado Magnani, Guido Pastore, Benedetto Terracini

Risultato della ricerca: Contributo su rivistaArticolo in rivistapeer review

Abstract

Aims and background: A cohort study was conducted in order to measure cause-specific mortality among parents of children recorded in the Childhood Cancer Registry of Piedmont. It is the first study carried out on the subject in southern Europe. Methods and study design: The study comprised the 740 children resident in Turin and in whom a cancer had been diagnosed in the period 1957-1991. Nominal data were obtained for 723 fathers and 733 mothers. At the end of the follow-up in 1995, 645 fathers were alive, 68 dead and 10 untraceable. Corresponding figures for mothers were 700, 28 and 5. Cause of death was known for 91 of 96 parents. Results: The period of observation of parents started on the birth of the index child, however mortality analyses were restricted to the period after 1965 because of limited availability of local reference rates. Total mortality was lower than expected among fathers (66 observed deaths vs 88.2 expected, P <0.05) and mothers (28 vs 31.4). Fathers showed deficits (not statistically significant) of lung neoplasms (4 vs 9.9), cardiovascular diseases (18 vs 27.1) and hepatic cirrhosis (2 vs 6.6). No statistically significant variations in mortality were observed with time from diagnosis or according to life status of the children. No cancer deaths occurred among the mothers of sarcoma cases whereas 1.9 were expected. Conclusions: The data do not indicate any increase in mortality from cancer or other causes and, on the contrary, show a reduction in mortality which was more evident for the causes related to life style.

Lingua originaleInglese
pagine (da-a)443-448
Numero di pagine6
RivistaTumori
Volume85
Numero di pubblicazione6
DOI
Stato di pubblicazionePubblicato - 1999
Pubblicato esternamente

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