TY - JOUR
T1 - Microbiota, Oxidative Stress, and Skin Cancer: An Unexpected Triangle
AU - AZZIMONTI, Barbara
AU - Ballacchino, Chiara
AU - Zanetta, Paola
AU - Cucci, Marie Angele
AU - Monge, Chiara
AU - Grattarola, Margherita
AU - Dianzani, Chiara
AU - Barrera, Giuseppina
AU - Pizzimenti, Stefania
N1 - Publisher Copyright:
© 2023 by the authors.
PY - 2023
Y1 - 2023
N2 - : Mounting evidence indicates that the microbiota, the unique combination of micro-organisms residing in a specific environment, plays an essential role in the development of a wide range of human diseases, including skin cancer. Moreover, a persistent imbalance of microbial community, named dysbiosis, can also be associated with oxidative stress, a well-known emerging force involved in the pathogenesis of several human diseases, including cutaneous malignancies. Although their interplay has been somewhat suggested, the connection between microbiota, oxidative stress, and skin cancer is a largely unexplored field. In the present review, we discuss the current knowledge on these topics, suggesting potential therapeutic strategies.
AB - : Mounting evidence indicates that the microbiota, the unique combination of micro-organisms residing in a specific environment, plays an essential role in the development of a wide range of human diseases, including skin cancer. Moreover, a persistent imbalance of microbial community, named dysbiosis, can also be associated with oxidative stress, a well-known emerging force involved in the pathogenesis of several human diseases, including cutaneous malignancies. Although their interplay has been somewhat suggested, the connection between microbiota, oxidative stress, and skin cancer is a largely unexplored field. In the present review, we discuss the current knowledge on these topics, suggesting potential therapeutic strategies.
KW - basal cell carcinoma
KW - keratinocyte carcinomas
KW - melanoma
KW - microbiota
KW - oxidative stress
KW - skin cancer
KW - squamous cell carcinoma
KW - basal cell carcinoma
KW - keratinocyte carcinomas
KW - melanoma
KW - microbiota
KW - oxidative stress
KW - skin cancer
KW - squamous cell carcinoma
UR - https://iris.uniupo.it/handle/11579/155705
U2 - 10.3390/antiox12030546
DO - 10.3390/antiox12030546
M3 - Article
SN - 2076-3921
VL - 12
JO - Antioxidants
JF - Antioxidants
IS - 3
ER -