Microbiota, Oxidative Stress, and Skin Cancer: An Unexpected Triangle

Barbara AZZIMONTI, Chiara Ballacchino, Paola Zanetta, Marie Angele Cucci, Chiara Monge, Margherita Grattarola, Chiara Dianzani, Giuseppina Barrera, Stefania Pizzimenti

Risultato della ricerca: Contributo su rivistaArticolo in rivistapeer review

Abstract

: Mounting evidence indicates that the microbiota, the unique combination of micro-organisms residing in a specific environment, plays an essential role in the development of a wide range of human diseases, including skin cancer. Moreover, a persistent imbalance of microbial community, named dysbiosis, can also be associated with oxidative stress, a well-known emerging force involved in the pathogenesis of several human diseases, including cutaneous malignancies. Although their interplay has been somewhat suggested, the connection between microbiota, oxidative stress, and skin cancer is a largely unexplored field. In the present review, we discuss the current knowledge on these topics, suggesting potential therapeutic strategies.
Lingua originaleInglese
RivistaAntioxidants
Volume12
Numero di pubblicazione3
DOI
Stato di pubblicazionePubblicato - 2023

Keywords

  • basal cell carcinoma
  • keratinocyte carcinomas
  • melanoma
  • microbiota
  • oxidative stress
  • skin cancer
  • squamous cell carcinoma

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