Methods for Measuring ctDNA in Lymphomas

Davide Rossi, Adalgisa Condoluci, Valeria Spina, Gianluca GAIDANO

Risultato della ricerca: Capitolo in libro/report/atti di convegnoContributo in volume (Capitolo o Saggio)peer review

Abstract

Plasma cell-free DNA (cfDNA) is an easily accessible source of tumor DNA that allows accurate profiling of lymphoma patients, representing a complementary source of tumor DNA to tissue biopsy for genotyping. Applications of cfDNA analysis in lymphomas include: (1) identification of tumor mutations in a biopsy-free manner; (2) tracking tumor clonal evolution and identification of mutations causing resistance to treatment; and (3) monitoring of residual disease after therapy.

Lingua originaleInglese
Titolo della pubblicazione ospiteMethods in molecular biology
Pagine253-265
Numero di pagine13
Volume1881
DOI
Stato di pubblicazionePubblicato - 2019

Keywords

  • Genetics
  • Genotyping
  • Liquid biopsy
  • Lymphomas
  • Molecular Biology
  • Next-generation sequencing
  • cfDNA

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