Mechanisms of H4/ICOS costimulation: Effects on proximal TCR signals and MAP kinase pathways

Keyphrases

• Interleukin-10 100%
• Costimulation 100%
• Interleukin-4 (IL-4) 100%
• Mitogen-activated Protein Kinase 100%
• TCR Signaling 100%
• ZAP70 80%
• Kinase Activation 80%
• Extracellular Signal-regulated Kinase 80%
• CD28 60%
• C-Jun N-terminal Kinase 60%
• P38 MAP Kinase 40%
• Th2 Cells 40%
• Cyclosporine 40%
• MAPK Inhibitors 20%
• Costimulatory Molecules 20%
• Tyrosine Phosphorylation 20%
• Phosphorylation 20%
• CD4+ 20%
• Phosphoinositide 3-kinase (PI3K) 20%
• PKC Inhibitor 20%
• Actin Polymerization 20%
• Cytochalasin D 20%
• TCR Activation 20%
• Jun N-terminal Kinase Inhibitor 20%
• Phosphatidylinositol 3-kinase Inhibitor 20%

Biochemistry, Genetics and Molecular Biology

• Mitogen-Activated Protein Kinase 100%
• Secretion (Process) 100%
• T Cell Receptor 100%
• Interleukin 10 100%
• Interleukin 4 100%
• ZAP70 80%
• N-Terminus 80%
• Extracellular Signal-Regulated Kinases 80%
• Kinase 60%
• Phosphotransferase 60%
• CD28 60%
• Ciclosporin 40%
• CD4 40%
• P38 Mitogen-Activated Protein Kinases 40%
• Tyrosine Phosphorylation 20%
• Phosphoinositide 3-Kinase 20%
• Actin Polymerization 20%
• Cross-Link 20%
• Phosphoinositide 3-Kinase Inhibitor 20%
• Mitogen-Activated Protein Kinase Kinase 20%

Immunology and Microbiology

• Secretion (Process) 100%
• Interleukin 10 100%
• T Cell Receptor 100%
• Interleukin 4 100%
• Amino Terminal Sequence 80%
• CD28 60%
• CD4 40%
• Th2 Cell 40%
• Ciclosporin 40%
• Cross Linking 20%
• Protein Phosphorylation 20%
• Actin Polymerization 20%
• CD3 Antigen 20%