Magnetic resonance and the diagnosis of short stature of hypothalamic‐hypophyseal origin

S. Vannelli, T. Avataneo, L. Benso, F. Potenzoni, S. Cirillo, M. Mostert, G. Bona

Risultato della ricerca: Contributo su rivistaArticolo in rivistapeer review

Abstract

Magnetic resonance imaging was performed in 23 patients with short stature (7 had multiple pituitary hormone defect, 11 had isolated growth hormone deficiency and 5 had normal variant short stature) to investigate if there is a relation between magnetic resonance findings and results of endocrine tests. Magnetic resonance imaging of patients with multiple pituitary hormone deficiency or with serious isolated growth hormone deficiency (growth hormone < 3 μg/l) revealed an interrupted pituitary stalk and ectopic neurohypophysis or a mass. In patients with less serious isolated growth hormone deficiency (growth hormone > 3 μg/l) or with normal variant short stature, the technique revealed a normal or hypoplastic hypophysis. Magnetic resonance appears to be a useful second‐level diagnostic tool in defining the type of alteration in growth defects of endocrine origin.

Lingua originaleInglese
pagine (da-a)155-161
Numero di pagine7
RivistaActa Paediatrica, International Journal of Paediatrics
Volume82
Numero di pubblicazione2
DOI
Stato di pubblicazionePubblicato - feb 1993
Pubblicato esternamente

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