TY - JOUR
T1 - Leaping the Boundaries in Laparoscopic Liver Surgery for Hepatocellular Carcinoma
AU - Cassese, Gianluca
AU - Han, Ho Seong
AU - Lee, Boram
AU - Lee, Hae Won
AU - Cho, Jai Young
AU - Troisi, Roberto
N1 - Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/4/1
Y1 - 2022/4/1
N2 - The minimally invasive approach for hepatocellular carcinoma (HCC) had a slower diffusion compared to other surgical fields, mainly due to inherent peculiarities regarding the risks of uncontrollable bleeding, oncological inadequacy, and the need for both laparoscopic and liver major skills. Recently, laparoscopic liver resection (LLR) has been associated with an improved postoperative course, including reduced postoperative decompensation, intraoperative blood losses, length of hospitalization, and unaltered oncological outcomes, leading to its adoption within international guidelines. However, LLR for HCC still faces several limitations, mainly linked to the impaired function of underlying parenchyma, tumor size and numbers, and difficult tumor position. The aim of this review is to highlight the state of the art and future perspectives of LLR for HCC, focusing on key points for overcoming currents limitations and pushing the boundaries in minimally invasive liver surgery (MILS).
AB - The minimally invasive approach for hepatocellular carcinoma (HCC) had a slower diffusion compared to other surgical fields, mainly due to inherent peculiarities regarding the risks of uncontrollable bleeding, oncological inadequacy, and the need for both laparoscopic and liver major skills. Recently, laparoscopic liver resection (LLR) has been associated with an improved postoperative course, including reduced postoperative decompensation, intraoperative blood losses, length of hospitalization, and unaltered oncological outcomes, leading to its adoption within international guidelines. However, LLR for HCC still faces several limitations, mainly linked to the impaired function of underlying parenchyma, tumor size and numbers, and difficult tumor position. The aim of this review is to highlight the state of the art and future perspectives of LLR for HCC, focusing on key points for overcoming currents limitations and pushing the boundaries in minimally invasive liver surgery (MILS).
KW - hepatocellular carcinoma
KW - laparoscopic liver resection
KW - minimally invasive liver surgery
KW - overcoming the limits
UR - http://www.scopus.com/inward/record.url?scp=85128244575&partnerID=8YFLogxK
U2 - 10.3390/cancers14082012
DO - 10.3390/cancers14082012
M3 - Review article
SN - 2072-6694
VL - 14
JO - Cancers
JF - Cancers
IS - 8
M1 - 2012
ER -
